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Major factors influencing cardiac output – heart rate and stroke volume, both of which are variable. [1]In cardiac physiology, cardiac output (CO), also known as heart output and often denoted by the symbols , ˙, or ˙, [2] is the volumetric flow rate of the heart's pumping output: that is, the volume of blood being pumped by a single ventricle of the heart, per unit time (usually measured ...
A Wiggers diagram, named after its developer, Carl Wiggers, is a unique diagram that has been used in teaching cardiac physiology for more than a century. [1] [2] In the Wiggers diagram, the X-axis is used to plot time subdivided into the cardiac phases, while the Y-axis typically contains the following on a single grid: Blood pressure. Aortic ...
Heart rate; Total peripheral resistance (primarily due to vasoconstriction of arteries) Inotropic state; In turn, this can have a significant impact upon several other variables: Stroke volume; Cardiac output; Pressure Pulse pressure (systolic pressure - diastolic pressure) Mean arterial pressure (usually approximated with diastolic pressure ...
In this case, the longitude is also called the right ascension of the ascending node (RAAN). The angle is measured eastwards (or, as seen from the north, counterclockwise) from the FPA to the node. [2] [3] An alternative is the local time of the ascending node (LTAN), based on the local mean time at which the
The resting heart rate of a newborn can be 120 beats per minute (bpm) and this gradually decreases until maturity and then gradually increases again with age. The adult resting heart rate ranges from 60 to 100 bpm. Exercise and fitness levels, age and basal metabolic rate can all affect the heart rate. An athlete's heart rate can be lower than ...
Due to the intrinsic property of myocardium that is responsible for the Frank-Starling mechanism, the heart can automatically accommodate an increase in venous return, at any heart rate. [ 1 ] [ 10 ] The mechanism is of functional importance because it serves to adapt left ventricular output to right ventricular output. [ 3 ]
This allows the heart to cope with the required cardiac output at a relatively low right atrial pressure. We get what is known as a family of cardiac function curves, as the heart rate increases before the plateau is reached, and without the RAP having to rise dramatically to stretch the heart more and get the Starling effect.
Therefore, using the assumed Fick determination, the approximated cardiac output for an average man (1.9 m3) is: Cardiac Output = (125 mL O 2 /minute × 1.9) / (200 mL O 2 /L − 150 mL O 2 /L) = 4.75 L/min. Cardiac output may also be estimated with the Fick principle using production of carbon dioxide as a marker substance. [3]