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Nicotine is unusual in comparison to most drugs, as its profile changes from stimulant to sedative with increasing dosages, a phenomenon known as "Nesbitt's paradox" after the doctor who first described it in 1969. [137] [138] At very high doses it dampens neuronal activity. [139] Nicotine induces both behavioral stimulation and anxiety in ...
Nicotine-only products — Nicotine-containing products that do not contain tobacco, featuring nicotine either extracted from tobacco or non-tobacco nicotine, usually synthetic nicotine. Common nicotine-only products include e-liquid ( aerosolized using an e-cigarette or vape ), nicotine pouches , and various types of nicotine replacement ...
Raw broccoli is 89% water, 7% carbohydrates, 3% protein, and contains negligible fat (table). A 100-gram ( 3 + 1 ⁄ 2 -ounce) reference amount of raw broccoli provides 141 kilojoules (34 kilocalories) of food energy and is a rich source (20% or higher of the Daily Value , DV) of vitamin C (107% DV) and vitamin K (97% DV) (table).
One cup of raw broccoli, for instance, contains magnesium, potassium, selenium, folate, vitamin A, vitamin C, vitamin K, nearly 2 grams of protein and close to 2 grams of dietary fiber, per the U ...
Does eating broccoli have side effects? Broccoli makes some people gassy and bloated. It contains raffinose, a type of sugar that isn't digested in the intestines. Instead, the gut bacteria use ...
“Nicotine pouches contain no tobacco leaf, so they are likely to have lower levels of toxicants compared to combustible cigarettes or smokeless tobacco,” Hrywna says. You also don’t inhale ...
Tobacco also contains 2,3,6-Trimethyl-1,4-naphthoquinone (sometimes called 2,3,6-TQ and TMN) which is a reversible monoamine oxidase inhibitor of type A and B with a binding affinity somewhat similar to that of clorgyline and deprenyl. It is a stronger dopamine releasing agent than nicotine and inhibits dopamine metabolism from its MAOI activity.
Although many of these additives are used in making cigarettes, each cigarette does not contain all of these additives. Some of these additives are found in cigarettes outside the USA too. [10] Some American brands are sold in other nations. For example: Marlboro, L&M, Winston, Chesterfield, Kent, and Newport. [11] [12