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A significant amount of research has been performed on glycosaminoglycans, especially glucosamine and chondroitin, for the treatment of arthritis.These compounds are commonly marketed as nutritional supplements and numerous 'soft therapeutic claims' are made about their health benefits - especially in aging populations. [1]
According to the Arthritis Foundation, glucosamine is one of the most popular supplements for managing arthritic joint pain. Glucosamine is a naturally occurring compound in the body that builds ...
Glucosamine is often sold in combination with other supplements such as chondroitin sulfate and methylsulfonylmethane. [citation needed] Glucosamine, along with commonly used chondroitin, is not routinely prescribed to treat people who have symptomatic osteoarthritis of the knee, as there is insufficient evidence that this treatment is helpful ...
The effectiveness of glucosamine is controversial. [149] Reviews have found it to be equal to [150] [151] or slightly better than placebo. [152] [153] A difference may exist between glucosamine sulfate and glucosamine hydrochloride, with glucosamine sulfate showing a benefit and glucosamine hydrochloride not. [154]
As of 2015 the largest trial conducted with the product was the Glucosamine and Chondroitin Arthritis Intervention Trial (GAIT), a double-blind, randomized, multicenter clinical trial sponsored by the US National Institutes of Health in 1583 people with knee osteoarthritis, which was published in the New England Journal of Medicine in 2006.
Arthritis and joint pain. ... glucosamine, chondroitin) Omega-3 fatty acids for skin and coat health ... Always carefully review policy documents and consult with insurance representatives to ...
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