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  2. Genetic disorder - Wikipedia

    en.wikipedia.org/wiki/Genetic_disorder

    Examples of this type of disorder are albinism, medium-chain acyl-CoA dehydrogenase deficiency, cystic fibrosis, sickle cell disease, Tay–Sachs disease, Niemann–Pick disease, spinal muscular atrophy, and Roberts syndrome. Certain other phenotypes, such as wet versus dry earwax, are also determined in an autosomal recessive fashion.

  3. Human genetics - Wikipedia

    en.wikipedia.org/wiki/Human_genetics

    Autosomal recessive inheritance, a 25% chance, and (purple) a 50% carrier chance. Autosomal recessive traits is one pattern of inheritance for a trait, disease, or disorder to be passed on through families. For a recessive trait or disease to be displayed two copies of the trait or disorder needs to be presented.

  4. Compound heterozygosity - Wikipedia

    en.wikipedia.org/wiki/Compound_heterozygosity

    In medical genetics, compound heterozygosity is the condition of having two or more heterogeneous recessive alleles at a particular locus that can cause genetic disease in a heterozygous state; that is, an organism is a compound heterozygote when it has two recessive alleles for the same gene, but with those two alleles being different from each other (for example, both alleles might be ...

  5. Dominance (genetics) - Wikipedia

    en.wikipedia.org/wiki/Dominance_(genetics)

    Autosomal dominant and autosomal recessive inheritance, the two most common Mendelian inheritance patterns. An autosome is any chromosome other than a sex chromosome.. In genetics, dominance is the phenomenon of one variant of a gene on a chromosome masking or overriding the effect of a different variant of the same gene on the other copy of the chromosome.

  6. Heredity - Wikipedia

    en.wikipedia.org/wiki/Heredity

    An example pedigree chart of an autosomal dominant disorder An example pedigree chart of an autosomal recessive disorder An example pedigree chart of a sex-linked disorder (The gene is on the X chromosome.) The description of a mode of biological inheritance consists of three main categories: 1. Number of involved loci

  7. Mucopolysaccharidosis - Wikipedia

    en.wikipedia.org/wiki/Mucopolysaccharidosis

    Approximately 1 in 100,000 newborns will experience severe mucopolysaccharidosis type I, while approximately 1 in 500,000 newborns will experience attenuated mucopolysaccharidosis type I. [2] Most mucopolysaccharidoses are autosomal recessive disorders, meaning that only individuals inheriting the defective gene from both parents are affected ...

  8. Autosome - Wikipedia

    en.wikipedia.org/wiki/Autosome

    Autosomal genetic disorders which exhibit Mendelian inheritance can be inherited either in an autosomal dominant or recessive fashion. [7] These disorders manifest in and are passed on by either sex with equal frequency. [7] [8] Autosomal dominant disorders are often present in both parent and child, as the child needs to inherit only one copy ...

  9. Race and health - Wikipedia

    en.wikipedia.org/wiki/Race_and_health

    There are many autosomal recessive single gene genetic disorders that differ in frequency between different populations due to the region and ancestry as well as the founder effect. Some examples of these disorders include: Cystic fibrosis, the most common life-limiting autosomal recessive disease among people of Northern European heritage