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A cohort study is a particular form of longitudinal study that samples a cohort (a group of people who share a defining characteristic, typically those who experienced a common event in a selected period, such as birth or graduation), performing a cross-section at intervals through time.
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Bioburden is normally defined as the number of bacteria living on a surface that has not been sterilized. [1]The term is most often used in the context of bioburden testing, also known as microbial limit testing, which is performed on pharmaceutical products and medical products for quality control purposes.
For curative treatments or rapidly changing conditions, cross-over trials may be infeasible or unethical. Crossover studies often have two problems: First is the issue of "order" effects, because it is possible that the order in which treatments are administered may affect the outcome. An example might be a drug with many adverse effects given ...
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Within the sciences, the word "contamination" can take on a variety of subtle differences in meaning, whether the contaminant is a solid or a liquid, [3] as well as the variance of environment the contaminant is found to be in. [2] A contaminant may even be more abstract, as in the case of an unwanted energy source that may interfere with a process. [2]
Interplanetary contamination refers to biological contamination of a planetary body by a space probe or spacecraft, either deliberate or unintentional. There are two types of interplanetary contamination: Forward contamination is the transfer of life and other forms of contamination from Earth to another celestial body.
In an ITT population, none of the patients are excluded and the patients are analyzed according to the randomization scheme. In other words, for the purposes of ITT analysis, everyone who is randomized in the trial is considered to be part of the trial regardless of whether he or she is dosed or completes the trial.