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  2. Cocaine dependence - Wikipedia

    en.wikipedia.org/wiki/Cocaine_dependence

    Cocaine is a powerful stimulant known to make users feel energetic, cheerful, talkative, etc. In time, negative side effects include increased body temperature, irregular or rapid heart rate, high blood pressure, increased risk of heart attacks, strokes and even sudden death from cardiac arrest.

  3. Epigenetics of cocaine addiction - Wikipedia

    en.wikipedia.org/wiki/Epigenetics_of_cocaine...

    CREB has been implicated in learning, memory, and depression and enriched in cocaine users within the nucleus accumbens. CREB seems to upregulate many genes in its pathway within the reward regions of the brain. It also seems to reduce the rewarding effects of cocaine and leads to depressive-like behaviors instead.

  4. As overdose rates rise, FDA calls for new medications to help ...

    www.aol.com/news/why-no-treatments-cocaine-meth...

    Cocaine and methamphetamine, for example, both increase levels of dopamine in the brain, albeit through different processes. As a result, people using cocaine may respond and behave very ...

  5. Drug rehabilitation - Wikipedia

    en.wikipedia.org/wiki/Drug_rehabilitation

    Drug rehabilitation is the process of medical or psychotherapeutic treatment for dependency on psychoactive substances such as alcohol, prescription drugs, and street drugs such as cannabis, cocaine, heroin, and amphetamines.

  6. Cocaine vaccine: could a promising treatment reach ... - AOL

    www.aol.com/news/2009-10-07-cocaine-vaccine...

    An experimental cocaine vaccine may help addicts end their addictions by inhibiting the drug's effects on the brain -- that is, preventing the high -- according to a National Institute on Drug ...

  7. Psychopharmacology - Wikipedia

    en.wikipedia.org/wiki/Psychopharmacology

    The effects of cocaine are similar to those of amphetamines, though cocaine tends to have a shorter duration of effect. In high doses or with prolonged use, cocaine can result in a number of negative effects, including irritability, anxiety, exhaustion, total insomnia, and even psychotic symptomatology.

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