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A study of 20 volunteers conducted at Nagoya University in Japan associated a higher degree of exercise-induced nausea after eating. [1] Lack of hydration during exercise is a well known cause of headache and nausea. [2] Exercising at a heavy rate causes blood flow to be taken away from the stomach, causing nausea. [3]
Exercise-associated hyponatremia (EAH) is a fluid-electrolyte disorder caused by a decrease in sodium levels (hyponatremia) during or up to 24 hours after prolonged physical activity. [1] This disorder can develop when marathon runners or endurance event athletes drink more fluid, usually water or sports drinks, than their kidneys can excrete. [2]
At the 2019 Perm International Marathon, Alexander Novikov finished first despite suffering from a bout of diarrhea, which left his clothes sodden. [11] At the 2024 Boston Marathon, Davis Clarke finished in 2 hours and 56 minutes after he soiled his shorts toward the end of the race. [12]
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The second wind phenomenon in GSD-V individuals can be demonstrated by measuring heart rate during a 12 Minute Walk Test. [21] [22] [23] A "third wind" phenomenon is also seen in GSD-V individuals, where after approximately 2 hours, they see a further improvement of symptoms as the body becomes even more fat adapted. [24] [25]
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Dylan Marx, 31, of San Diego,, finished second in the Two Cities Half Marathon on Nov. 5, 2023 in 2:17:46.96. In 2020, he placed 35th at the Olympic marathon trials and has since battled injuries.
Unless glycogen stores are replenished during exercise, glycogen stores in such an individual will be depleted after less than 2 hours of continuous cycling [11] or 15 miles (24 km) of running. Training and carbohydrate loading can raise these reserves as high as 880 g (3600 kcal), correspondingly raising the potential for uninterrupted exercise.