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Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity, such as from a spinal cord injury or multiple sclerosis. [ 8 ] [ 9 ] It may also be used for hiccups and muscle spasms near the end of life, [ 9 ] and off-label to treat alcohol use disorder [ 10 ] [ 11 ] or opioid withdrawal symptoms. [ 12 ]
In 2008, Ameisen wrote a best-selling book, The End Of My Addiction, published in France as Le Dernier Verre (The Last Glass), describing his experience of curing his alcoholism with baclofen. [6] In 2007, an Italian team also showed the effectiveness and the safety of baclofen as a treatment for alcohol addiction. [7]
Le Dernier Verre (French for "The Last Glass") is a best-selling book by French cardiologist Olivier Ameisen that was published in 2008 and describes the author's experience of curing himself of alcoholism using the muscle relaxant, baclofen. [1] The book has been translated to English as The End of My Addiction, and German as Das Ende meiner ...
A Radiographer explains an x-ray to a coal miner participating in screening. Patient education can include explaining the results of diagnostic tests. Patient education is a planned interactive learning process designed to support and enable expert patients [1] to manage their life with a disease and/or optimise their health and well-being. [2] [3]
This is usually placed in the left abdomen. It is a pump that is connected to the spinal cord, whereby it releases doses of baclofen to alleviate continuous muscle flexion. Baclofen is a muscle relaxant and is often given by mouth to people to help counter the effects of spasticity, although this has the side effect of sedating the individual. [69]
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No conclusions can be drawn concerning the efficacy or safety of baclofen for alcohol withdrawal syndrome due to the insufficiency and low quality of the evidence. [ 45 ] Antipsychotics , such as haloperidol , are sometimes used in addition to benzodiazepines to control agitation or psychosis. [ 12 ]
Baclofen, an agonist of the GABA B receptor, while effective, has similar issues of needing frequent dosing in addition to greater adverse effects compared to other ...