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Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity, such as from a spinal cord injury or multiple sclerosis. [ 8 ] [ 9 ] It may also be used for hiccups and muscle spasms near the end of life, [ 9 ] and off-label to treat alcohol use disorder [ 10 ] [ 11 ] or opioid withdrawal symptoms. [ 12 ]
In 2008, Ameisen wrote a best-selling book, The End Of My Addiction, published in France as Le Dernier Verre (The Last Glass), describing his experience of curing his alcoholism with baclofen. [6] In 2007, an Italian team also showed the effectiveness and the safety of baclofen as a treatment for alcohol addiction. [7]
This is usually placed in the left abdomen. It is a pump that is connected to the spinal cord, whereby it releases doses of baclofen to alleviate continuous muscle flexion. Baclofen is a muscle relaxant and is often given by mouth to people to help counter the effects of spasticity, although this has the side effect of sedating the individual. [69]
Baclofen, diazepam and dantrolene remain the three most commonly used pharmacologic agents in the treatment of spastic hypertonia. Baclofen is generally the drug of choice for spinal cord types of spasticity, while sodium dantrolene is the only agent which acts directly on muscle tissue. Tizanidine is also available.
A Radiographer explains an x-ray to a coal miner participating in screening. Patient education can include explaining the results of diagnostic tests. Patient education is a planned interactive learning process designed to support and enable expert patients [1] to manage their life with a disease and/or optimise their health and well-being. [2] [3]
Le Dernier Verre (French for "The Last Glass") is a best-selling book by French cardiologist Olivier Ameisen that was published in 2008 and describes the author's experience of curing himself of alcoholism using the muscle relaxant, baclofen. [1] The book has been translated to English as The End of My Addiction, and German as Das Ende meiner ...
There is evidence, albeit limited, of the clinical effectiveness of THC and CBD extracts, [126] baclofen, [127] dantrolene, [128] diazepam, [129] and tizanidine. [130] [131] [132] In the most complicated cases intrathecal injections of baclofen can be used. [133] There are also palliative measures like castings, splints or customized seatings. [31]
No conclusions can be drawn concerning the efficacy or safety of baclofen for alcohol withdrawal syndrome due to the insufficiency and low quality of the evidence. [ 45 ] Antipsychotics , such as haloperidol , are sometimes used in addition to benzodiazepines to control agitation or psychosis. [ 12 ]