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Adult-use cannabis can only be sold in packages of a single color without graphics other than the logo and a health warning. [9] Cannabis companies in Canada are not allowed to promote themselves through TV commercials, billboards, or glossy magazine ads, sponsor people or events, or put their names on sports and cultural facilities. [10]
These are achieved at lower doses, because many synthetic cannabinoids are more potent than marijuana, and users are often unaware of exactly what they are getting and how potent it is. [55] For example, Δ 9-THC has an EC 50 of 250 nM at CB 1 and 1157 nM at CB 2, whereas PB-22 has an EC 50 of 5.1 nM at CB 1 and 37 nM at CB 2. [8]
THC is just one of more than 100 identified cannabinoid compounds in Cannabis, which also include cannabinol (CBN) and cannabidiol (CBD). Cannabis plants vary widely, with different strains producing dynamic balances of cannabinoids (THC, CBD, etc.) and yielding markedly different effects. Popular strains are often hybrids of C. sativa and C ...
Nabiximols [2] sold under the brand name Sativex, is a specific Cannabis extract that was approved in 2010 as a botanical drug in the United Kingdom. Nabiximols is sold as a mouth spray intended to alleviate neuropathic pain , spasticity , overactive bladder , and other symptoms of multiple sclerosis ; it was developed by the UK company GW ...
Cannabis ruderalis has naturally low concentrations of THC. With hybrid breeding, autoflowering plants can contain levels of THC similar to the strain they're bred with. [13] [2] [14] Breeders have reported THC content around 25% in some newer varieties while many varieties also have high CBD content. [15] [16] Some advantages of autoflower ...
Hashish remains in high demand in most of the world while quality continues to increase, due to many Moroccan and western farmers in Morocco and other hash producing countries using more advanced cultivation methods as well as cultivating further developed cannabis strains which increases yields greatly, as well as improving resin quality with ...
Consequently, a high-fat meal increases levels of 11-hydroxy-THC by only 25% and most of the increase in bioavailability is due to increased levels of THC. [31] The bioavailability of THC when smoking or inhaling is approximately 25%, with a range of 2% to 56% (although most commonly between 10 and 35%).
Its most common form is the oromucosal spray derived from two strains of Cannabis sativa and containing THC and CBD traded under the brand name Sativex®. [53] It is not approved in the United States, but is approved in several European countries, Canada, and New Zealand as of 2013.