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  2. Doxycycline - Wikipedia

    en.wikipedia.org/wiki/Doxycycline

    Doxycycline, doxycycline monohydrate and doxycycline hyclate are yellow, crystalline powders with a bitter taste. The latter smells faintly of ethanol , a 1% aqueous solution has a pH of 2–3, and the specific rotation is [ α ] D 25 {\displaystyle [\alpha ]_{D}^{25}} −110° cm 3 /dm·g in 0.01 N methanolic hydrochloric acid .

  3. Metalloprotease inhibitor - Wikipedia

    en.wikipedia.org/wiki/Metalloprotease_inhibitor

    Thus far, Periostat (active ingredient is doxycycline hyclate) is the only MMP inhibitor that has been approved by the U.S. Food and Drug Administration (FDA). It is used for the treatment of periodontitis. Other MMP inhibitors have exhibited serious side effects during preclinical trials. These side effects are caused by insufficient selectivity.

  4. Tetracycline antibiotics - Wikipedia

    en.wikipedia.org/wiki/Tetracycline_antibiotics

    Side-effects from tetracyclines are not common, but of particular note is phototoxicity. It increases the risk of sunburn under exposure to light from the sun or other sources. This may be of particular importance for those intending to take on vacations long-term doxycycline as a malaria prophylaxis.

  5. Perioral dermatitis - Wikipedia

    en.wikipedia.org/wiki/Perioral_dermatitis

    Doxycycline is most often the first antibiotic drug choice, given at a daily dosage of 100 mg for up to a month before considering tapering off or stopping. Sometimes, longer duration of low doses of doxycycline are required. [8] Possible side effects of doxycycline include gastrointestinal issues and irritation in the esophagus. [27]

  6. Metacycline - Wikipedia

    en.wikipedia.org/wiki/Metacycline

    It is used as a precursor in the industrial synthesis of doxycycline hyclate. [citation needed] It has been found to act as an agonist of the human pregnane X receptor ligand-binding domain and to induce CYP3A4 expression in vitro. [1]

  7. Hyclate - Wikipedia

    en.wikipedia.org/wiki/Hyclate

    A hyclate (Latin: hyclas) is a pharmaceutical term for hydrochloride hemiethanolate hemihydrate [1] [2] (·HCl· ⁠ 1 / 2 ⁠ EtOH· ⁠ 1 / 2 ⁠ H 2 O), e.g. doxycycline hyclate. [ 3 ] [ 4 ] References

  8. Talk:Doxycycline - Wikipedia

    en.wikipedia.org/wiki/Talk:Doxycycline

    Here are links to possibly useful sources of information about Doxycycline. PubMed provides review articles from the past five years (limit to free review articles) The TRIP database provides clinical publications about evidence-based medicine. Other potential sources include: Centre for Reviews and Dissemination and CDC

  9. Rosacea - Wikipedia

    en.wikipedia.org/wiki/Rosacea

    Systemic doxycycline modified-release capsules are commonly used for the treatment of rosacea. The capsules are taken orally once daily, usually in a low dose, to achieve anti-inflammatory effects. Doxycycline acts by inhibiting inflammation and reducing the production of reactive oxygen species associated with rosacea symptoms.

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