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Perianal cellulitis, also known as perianitis or perianal streptococcal dermatitis, is a bacterial infection affecting the lower layers of the skin around the anus. [ 1 ] [ 2 ] [ 3 ] It presents as bright redness in the skin and can be accompanied by pain, difficulty defecating, itching, and bleeding.
Rectal biopsies of acute radiation proctopathy show superficial depletion of epithelial cells and acute inflammatory cells located in the lamina propria. [4] By contrast, rectal biopsies of RAVE and chronic radiation proctopathy demonstrates ischemic endarteritis of the submucosal arterioles, submucosal fibrosis, and neovascularization.
Colonoscopy shows erythema of the colonic mucosa, which may be characterized by friability and exudate. [1] The descending and sigmoid colon are typically involved. Biopsies of the affected area and the unaffected rectum confirm the diagnosis. [1] Biopsies of SCAD show evidence of chronic inflammation. Rectal biopsies show normal mucosa.
Pouchitis is an umbrella term for inflammation of the ileal pouch, an artificial rectum surgically created out of ileum (the last section of the small intestine) in patients who have undergone a proctocolectomy or total colectomy (removal of the colon and rectum). [1]
This involves removing the large majority of the remaining rectal stump and creating a new "rectum" by fashioning the end of the small intestine into a pouch and attaching it to the anus. After this procedure, a new type of ileostomy is created (known as a loop ileostomy) to allow the anastomoses to heal.
Pruritus ani is the irritation of the skin at the exit of the rectum, known as the anus, causing the desire to scratch. [1] The intensity of anal itching increases from moisture, [2] pressure, and rubbing caused by clothing and sitting. At worst, anal itching causes intolerable discomfort that often is accompanied by burning and soreness.
Erythema (Ancient Greek: ἐρύθημα, from Greek erythros 'red') is redness of the skin or mucous membranes, caused by hyperemia (increased blood flow) in superficial capillaries. [1] It occurs with any skin injury, infection, or inflammation. Examples of erythema not associated with pathology include nervous blushes. [2]
In contrast to cellulitis, erysipelas is a bacterial infection involving the more superficial layers of the skin, present with an area of redness with well-defined edges, and more often is associated with a fever. [1] The diagnosis is usually based on the presenting signs and symptoms, while a cell culture is rarely possible.