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Carbon tetrachloride, also known by many other names (such as carbon tet for short and tetrachloromethane, also recognised by the IUPAC), is a chemical compound with the chemical formula CCl 4. It is a non-flammable, dense, colourless liquid with a "sweet" chloroform-like odour that can be detected at low levels.
A hepatotoxin (Gr., hepato = liver) is a toxic chemical substance that damages the liver.. It can be a side-effect, but hepatotoxins are also found naturally, such as microcystins and pyrrolizidine alkaloids, or in laboratory environments, such as carbon tetrachloride, or far more pervasively in the form of ethanol (drinking alcohol).
Carbon tetrachloride is commonly used to induce acute type A liver injury in animal models. Idiosyncratic (type B) injury occurs without warning, when agents cause non-predictable hepatotoxicity in susceptible individuals, which is not related to dose and has a variable latency period. [8]
The handling of this chemical may incur notable safety precautions. It is highly recommend that you seek the Material Safety Datasheet for this chemical from a reliable source such as SIRI, and follow its directions.
Faraday was previously falsely credited for the synthesis of tetrachloroethylene, which in reality, was carbon tetrachloride. [non-primary source needed] While trying to make Faraday's "protochloride of carbon", Regnault found that his compound was different from Faraday's. Victor Regnault stated "According to Faraday, the chloride of carbon ...
In addition, a variety of simple chlorinated hydrocarbons including dichloromethane, chloroform, and carbon tetrachloride have been isolated from marine algae. [7] A majority of the chloromethane in the environment is produced naturally by biological decomposition, forest fires, and volcanoes. [8]
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Carbon tetrachloride (CCl 4) can turn into phosgene when exposed to heat in air. This was a problem as carbon tetrachloride is an effective fire suppressant and was formerly in widespread use in fire extinguishers. [15] There are reports of fatalities caused by its use to fight fires in confined spaces. [16]