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Calcification is the accumulation of calcium salts in a body tissue. It normally occurs in the formation of bone, but calcium can be deposited abnormally in soft tissue, [1] [2] causing it to harden. Calcifications may be classified on whether there is mineral balance or not, and the location of the calcification. [3]
Ectopic calcification is a pathologic deposition of calcium salts in tissues or bone growth in soft tissues.This can be a symptom of hyperphosphatemia.Formation of osseous tissue in soft tissues such as the lungs, eyes, arteries, or other organs is known as ectopic calcification, dystrophic calcification, or ectopic ossification.
An enthesophyte, consisting of calcification deposits within the Achilles tendon at its calcaneal insertion. The Achilles tendon is wider than normal, further suggesting inflammation. Enthesophytes are abnormal bony projections at the attachment of a tendon or ligament. [1]
Calcific tendinitis is a common condition where deposits of calcium phosphate form in a tendon, sometimes causing pain at the affected site. Deposits can occur in several places in the body, but are by far most common in the rotator cuff of the shoulder. Around 80% of those with deposits experience symptoms, typically chronic pain during ...
Dystrophic calcinosis cutis is the most prevalent kind of calcification on the skin. [2] The ectopic calcified mass usually consists of amorphous calcium phosphate and hydroxyapatite. [6] Dystrophic calcification is linked to a number of illnesses, such as infections, hereditary diseases, cutaneous neoplasms, and connective tissue diseases. [7]
In dystrophic calcification, basophilic calcium salt deposits aggregate, first in the mitochondria, then progressively throughout the cell. [citation needed] These calcifications are an indication of previous microscopic cell injury, occurring in areas of cell necrosis when activated phosphatases bind calcium ions to phospholipids in the membrane.
Tophi is when uric acid crystals around the joints form larger, hard deposits. It can lead to pain, soft tissue damage, and joint deformities. Folks with gout are more prone to certain other ...
A calcaneal spur (also known as a heel spur) is a bony outgrowth from the calcaneal tuberosity (heel bone). [1] Calcaneal spurs are typically detected by x-ray examination. [2] It is a form of exostosis. When a foot is exposed to constant stress, calcium deposits build up on the bottom of the heel bone. Generally, this has no effect on a person ...