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  2. Michele Kang - Wikipedia

    en.wikipedia.org/wiki/Michele_Kang

    In 2008, Kang founded Cognosante "to disrupt and challenge the status quo in the U.S. healthcare system". [12] The corporation works with federal and state health agencies to "expand access to care, improve care delivery, address social determinants of health, and ensure safety and security through multi-faceted technology and customer ...

  3. List of breast cancer cell lines - Wikipedia

    en.wikipedia.org/wiki/List_of_breast_cancer_cell...

    Scientists study the behaviour of isolated cells grown in the laboratory for insights into how cells function in the body in health and disease. Experiments using cell culture are used for developing new diagnostic tests and new treatments for diseases. This is a list of major breast cancer cell lines that are primarily used in breast cancer ...

  4. Antineoplastic resistance - Wikipedia

    en.wikipedia.org/wiki/Antineoplastic_resistance

    Cancer cell heterogeneity can cause disease progression when molecularly targeted therapy, fails to kill those tumor cells which do not express the marker, then divide and mutate further, creating a new heterogeneous tumour. In breast cancer models of the mouse the immune microenvironment affects susceptibility to neoadjuvant chemotherapy. In ...

  5. The Hallmarks of Cancer - Wikipedia

    en.wikipedia.org/wiki/The_Hallmarks_of_Cancer

    Cancer cells have defects in the control mechanisms that govern how often they divide, and in the feedback systems that regulate these control mechanisms (i.e. defects in homeostasis). Normal cells grow and divide, but have many controls on that growth. They only grow when stimulated by growth factors.

  6. MCF-7 - Wikipedia

    en.wikipedia.org/wiki/MCF-7

    MCF-7 is a breast cancer cell line isolated in 1970 from a 69-year-old White woman. [1] MCF-7 is the acronym of Michigan Cancer Foundation-7, referring to the institute in Detroit where the cell line was established in 1973 by Herbert Soule and co-workers. [2] The Michigan Cancer Foundation is now known as the Barbara Ann Karmanos Cancer ...

  7. Malignant transformation - Wikipedia

    en.wikipedia.org/wiki/Malignant_transformation

    Colon cancer provides one example of the mechanisms by which diet, the top factor listed in the table, is an external factor in cancer. The Western diet of African Americans in the United States is associated with a yearly colon cancer rate of 65 per 100,000 individuals, while the high fiber/low fat diet of rural Native Africans in South Africa is associated with a yearly colon cancer rate of ...

  8. Carcinogenesis - Wikipedia

    en.wikipedia.org/wiki/Carcinogenesis

    The cancer stem cell hypothesis proposes that the different kinds of cells in a heterogeneous tumor arise from a single cell, termed Cancer Stem Cell. Cancer stem cells may arise from transformation of adult stem cells or differentiated cells within a body. These cells persist as a subcomponent of the tumor and retain key stem cell properties.

  9. Living Proof (2008 film) - Wikipedia

    en.wikipedia.org/wiki/Living_Proof_(2008_film)

    Teleplay writer Vivienne Radkoff had the story for about seven years before it was completed. It is an adaptation of Robert Bazell's book HER-2: The Making of Herceptin, a Revolutionary Treatment for Breast Cancer. The film was the first mainstream feature film to be scored as a solo project by composer Halli Cauthery.