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  2. Recreational use of dextromethorphan - Wikipedia

    en.wikipedia.org/wiki/Recreational_use_of_dext...

    Recreational use of dextromethorphan. Dextromethorphan, or DXM, a common active ingredient found in many over-the-counter cough suppressant cold medicines, is used as a recreational drug and entheogen for its dissociative effects. [1] Street names include Brownies, Dextro, Drix, Gel, Groove, Lean, Mega-perls, Poor man's ecstasy, Poor man's PCP ...

  3. Hydrocodone/paracetamol - Wikipedia

    en.wikipedia.org/wiki/Hydrocodone/paracetamol

    In August 2014, the Drug Enforcement Administration (DEA) announced that all hydrocodone combination products (HCPs) will be rescheduled from schedule III to schedule II of the Controlled Substances Act (CSA), effective in October 2014. [11] In 2010, more than 16,000 deaths were attributed to abuse of opioid drugs. [11]

  4. Lean (drug) - Wikipedia

    en.wikipedia.org/wiki/Lean_(drug)

    Dextromethorphan syrup. Lean or purple drank (known by numerous local and street names) is a polysubstance drink used as a recreational drug. It is prepared by mixing prescription-grade cough or cold syrup containing an opioid drug and an anti-histamine drug with a soft drink and sometimes hard candy.

  5. Switching Antidepressants: Safety, Side Effects & Other ... - AOL

    www.aol.com/switching-antidepressants-safety...

    Some of the most common reasons to change antidepressants include: Side effects. Many antidepressants can cause side effects, including nausea, digestive issues, headaches and difficulty sleeping ...

  6. Polysubstance use - Wikipedia

    en.wikipedia.org/wiki/Polysubstance_use

    Polysubstance use or poly drug use refers to the use of combined psychoactive substances. Polysubstance use may be used for entheogenic, recreational, or off-label indications, with both legal and illegal substances. In many cases one drug is used as a base or primary drug, with additional drugs to leaven or compensate for the side effects, or ...

  7. Codeine/paracetamol - Wikipedia

    en.wikipedia.org/wiki/Codeine/paracetamol

    Codeine/paracetamol, also called codeine/acetaminophen and co-codamol, is a compound analgesic, comprising codeine phosphate and paracetamol (acetaminophen). Codeine/paracetamol is used for the relief of mild to moderate pain when paracetamol or non-steroidal anti-inflammatory drugs (NSAIDs; such as ibuprofen, aspirin, and naproxen) alone do not sufficiently relieve symptoms.

  8. Paradoxical reaction - Wikipedia

    en.wikipedia.org/wiki/Paradoxical_reaction

    Paradoxical reaction. A paradoxical reaction (or paradoxical effect) is an effect of a chemical substance, such as a medical drug, that is opposite to what would usually be expected. An example of a paradoxical reaction is pain caused by a pain relief medication.

  9. Psychoactive drug - Wikipedia

    en.wikipedia.org/wiki/Psychoactive_drug

    Psychoactive drugs operate by temporarily affecting a person's neurochemistry, which in turn causes changes in a person's mood, cognition, perception and behavior. There are many ways in which psychoactive drugs can affect the brain. Each drug has a specific action on one or more neurotransmitter or neuroreceptor in the brain.