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  2. Penicillin - Wikipedia

    en.wikipedia.org/wiki/Penicillin

    Kidneys. Penicillins (P, PCN or PEN) are a group of β-lactam antibiotics originally obtained from Penicillium moulds, principally P. chrysogenum and P. rubens. Most penicillins in clinical use are synthesised by P. chrysogenum using deep tank fermentation [2] and then purified. [3][4] A number of natural penicillins have been discovered, but ...

  3. History of penicillin - Wikipedia

    en.wikipedia.org/wiki/History_of_penicillin

    The history of penicillin follows observations and discoveries of evidence of antibiotic activity of the mould Penicillium that led to the development of penicillins that became the first widely used antibiotics. Following the production of a relatively pure compound in 1942, penicillin was the first naturally-derived antibiotic.

  4. β-Lactam antibiotic - Wikipedia

    en.wikipedia.org/wiki/Beta-lactam_antibiotics

    β-Lactam antibiotics are indicated for the prevention and treatment of bacterial infections caused by susceptible organisms. At first, β-lactam antibiotics were mainly active only against gram-positive bacteria, yet the recent development of broad-spectrum β-lactam antibiotics active against various gram-negative organisms has increased their usefulness.

  5. Discovery of penicillin - Wikipedia

    en.wikipedia.org/wiki/Discovery_of_penicillin

    The discovery of penicillin was one of the most important scientific discoveries in the history of medicine. Ancient societies used moulds to treat infections and in the following centuries many people observed the inhibition of bacterial growth by moulds. While working at St Mary's Hospital in London in 1928, Scottish physician Alexander ...

  6. Antibiotic - Wikipedia

    en.wikipedia.org/wiki/Antibiotic

    Legal status. In Wikidata. An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of such infections. [1][2] They may either kill or inhibit the growth of bacteria.

  7. Benzylpenicillin - Wikipedia

    en.wikipedia.org/wiki/Benzylpenicillin

    Benzylpenicillin, also known as penicillin G (PenG [4]) or BENPEN, [5] is an antibiotic used to treat a number of bacterial infections. [6] This includes pneumonia , strep throat , syphilis , necrotizing enterocolitis , diphtheria , gas gangrene , leptospirosis , cellulitis , and tetanus . [ 6 ]

  8. β-Lactam - Wikipedia

    en.wikipedia.org/wiki/Beta-lactam

    A beta-lactam (β-lactam) ring is a four-membered lactam. [1] A lactam is a cyclic amide, and beta -lactams are named so because the nitrogen atom is attached to the β-carbon atom relative to the carbonyl. The simplest β-lactam possible is 2-azetidinone. β-lactams are significant structural units of medicines as manifested in many β-lactam ...

  9. Ampicillin - Wikipedia

    en.wikipedia.org/wiki/Ampicillin

    Ampicillin is an antibiotic belonging to the aminopenicillin class of the penicillin family. The drug is used to prevent and treat a number of bacterial infections, such as respiratory tract infections, urinary tract infections, meningitis, salmonellosis, and endocarditis. [ 7 ]

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