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The size difference causes the difference in colors. Colloidal gold is a sol or colloidal suspension of nanoparticles of gold in a fluid, usually water. [ 1 ] The colloid is coloured usually either wine red (for spherical particles less than 100 nm) or blue-purple (for larger spherical particles or nanorods). [ 2 ]
Gold nanoparticles in chemotherapy and radiotherapy is the use of colloidal gold in therapeutic treatments, often for cancer or arthritis. Gold nanoparticle technology shows promise in the advancement of cancer treatments. Some of the properties that gold nanoparticles possess, such as small size, non-toxicity and non-immunogenicity make these ...
Nanoparticle drug delivery systems are engineered technologies that use nanoparticles for the targeted delivery and controlled release of therapeutic agents. The modern form of a drug delivery system should minimize side-effects and reduce both dosage and dosage frequency. Recently, nanoparticles have aroused attention due to their potential ...
Gold nanoparticles can be purchased or synthesized via a variety of methods. [12] Several strategies exist for functionalizing gold nanoparticles with single-stranded DNA; one of the most commonly utilized strategies involves introducing thiol-terminated DNA to a solution of gold nanoparticles and gradually increasing the concentration of a salt, like NaCl.
Immunogold labeling or immunogold staining (IGS) is a staining technique used in electron microscopy. [2] This staining technique is an equivalent of the indirect immunofluorescence technique for visible light. Colloidal gold particles are most often attached to secondary antibodies which are in turn attached to primary antibodies designed to ...
Gold nanoparticle-based optical sensors can be used to detect heavy metals very precisely; for example, mercury levels as low as 0.49 nanometers. This sensing modality takes advantage of FRET, in which the presence of metals inhibits the interaction between quantum dots and gold nanoparticles, and quenches the FRET response. [39]
Nanomedicine is the medical application of nanotechnology. [ 1 ] Nanomedicine ranges from the medical applications of nanomaterials and biological devices, to nanoelectronic biosensors, and even possible future applications of molecular nanotechnology such as biological machines. Current problems for nanomedicine involve understanding the ...
Gold Nanocages are hollow, porous gold nanoparticles ranging in size from 10 to over 150 nm. They are created by reacting silver nanoparticles with chloroauric acid (H Au Cl 4) in boiling water. [1] Whereas gold nanoparticles absorb light in the visible spectrum of light (at about 550 nm), gold nanocages absorb light in the near-infrared, [2 ...