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Hepatocyte growth factor receptor (HGF receptor) [5] [6] is a protein that in humans is encoded by the MET gene. The protein possesses tyrosine kinase activity. [ 7 ] The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor.
The hepatocyte plates are one cell thick in mammals and two cells thick in the chicken. Sinusoids display a discontinuous, fenestrated endothelial cell lining. The endothelial cells have no basement membrane and are separated from the hepatocytes by the space of Disse, which drains lymph into the portal tract lymphatics. [citation needed]
HepaRG cell line is a human hepatic in vitro line used in liver biology research and for assessing liver pathology, hepatotoxicity, and drug-induced injury. The HepaRG model is considered a surrogate for Primary Human Hepatocytes, which are the most pertinent model to reproduce the human liver functioning as they express 99% of the same genes .
Hepatocyte growth factor (HGF) or scatter factor (SF) is a paracrine cellular growth, motility and morphogenic factor. It is secreted by mesenchymal cells and targets and acts primarily upon epithelial cells and endothelial cells , but also acts on haemopoietic progenitor cells and T cells .
Cancer and Genetics Research Complex [1] is an interdisciplinary research center located at the University of Florida (UF). The goal of this facility is "to harness the diverse academic talents and resources of the genetic research community at UF to improve the health and well-being of our citizenry."
The first cancer research center director was John Ultmann whose specialty was the diagnosis, staging and treatment of Hodgkin's disease and non-Hodgkin's lymphoma, and the development of cancer chemotherapy. [4] The director is Kunle Odunsi, MD [5] who accepted the position in 2021. Odunsi is an expert in immunotherapy and vaccine therapy for ...
Databases for oncogenomic research are biological databases dedicated to cancer data and oncogenomic research. They can be a primary source of cancer data, offer a certain level of analysis (processed data) or even offer online data mining .
It is a component of the University of Texas Health Science Center, San Antonio which is located adjacently. The center serves more than 4.4 million people in the high-growth corridor of Central and South Texas including Austin , San Antonio , Laredo and the Rio Grande Valley , and handles more than 120,000 patient visits each year, and has a ...