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De Quervain's thyroiditis, also known as subacute granulomatous thyroiditis or giant cell thyroiditis, is a self-limiting inflammatory illness of the thyroid gland. [1] De Quervain thyroiditis is characterized by fever, flu-like symptoms, a painful goiter, and neck pain.
Thyroiditis is generally caused by an immune system attack on the thyroid, resulting in inflammation and damage to the thyroid cells. This disease is often considered a malfunction of the immune system and can be associated with IgG4-related systemic disease, in which symptoms of autoimmune pancreatitis, retroperitoneal fibrosis and noninfectious aortitis also occur.
In most cases AIT is characterized by onset of pain, firmness, tenderness, redness or swelling in the anterior aspect of the neck. [4] Patients will also present with a sudden fever, difficulty swallowing and difficulty controlling the voice. [5] Symptoms may be present from 1 to 180 days, with most symptoms lasting an average of about 18 days.
Thyroid disease is a medical condition that affects the structure and/or function of the thyroid gland. The thyroid gland is located at the front of the neck and produces thyroid hormones [1] that travel through the blood to help regulate many other organs, meaning that it is an endocrine organ. These hormones normally act in the body to ...
A goiter is a diffuse, often symmetric, swelling of the thyroid gland visible in the anterior neck that may develop. [13] The thyroid gland may become firm, large, and lobulated in Hashimoto's thyroiditis, but changes in the thyroid can also be non-palpable. [14] Enlargement of the thyroid is due to lymphocytic infiltration, and fibrosis. [15]
A possible explanation for the mental symptoms of sub-clinical thyroid disease, might be found in the fact that the brain has among the highest expression of THR's [clarification needed], and that neurons are often more sensitive than other tissues to thyroid abnormalities, including sub-clinical hyperthyroidism and thyrotoxicosis.
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The thyrohyoid muscle is innervated (along with the geniohyoid muscle [1] [3]: 457, 709 ) by a branch of the cervical plexus [4] [3]: 538 - the nerve to thyrohyoid muscle (thyrohyoid branch of ansa cervicalis) [4] - which is formed by fibres of the cervical spinal nerve 1 (C1) [1] [2] [3]: 538 (and - according to some sources - cervical spinal nerve 2 as well [4] [3]: 457 ) that join and ...
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