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  2. Calcium channel blocker toxicity - Wikipedia

    en.wikipedia.org/wiki/Calcium_channel_blocker...

    Within 6 hours [2] Causes: Too much calcium channel blockers either by accident or on purpose [3] Differential diagnosis: Beta blocker toxicity [1] Treatment: Activated charcoal, whole bowel irrigation, intravenous fluids, calcium gluconate, glucagon, high dose insulin, vasopressors, lipid emulsion [1] [2] Prognosis: High risk of death [2 ...

  3. Opioid overdose - Wikipedia

    en.wikipedia.org/wiki/Opioid_overdose

    Concerning the 2017 data in the charts below, deaths from the various drugs add up to more than 70,200 because multiple drugs are involved in many of the deaths. [2] According to the National Safety Council, the lifetime odds of dying from an overdose in the United States is 1 in 96. [68] Drug overdose deaths in the US per 100,000 people by state.

  4. Clark's rule - Wikipedia

    en.wikipedia.org/wiki/Clark's_rule

    Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK, the West Indies ...

  5. Benadryl challenge - Wikipedia

    en.wikipedia.org/wiki/Benadryl_challenge

    The recommended dosage of Benadryl tablets for adults is 1 to 2 tablets every 4 to 6 hours, [1] and only 1 tablet every 4 to 6 hours for children under the age of 12. [2]The Benadryl challenge is an internet challenge that emerged in 2020, revolving around the deliberate consumption, excessive use and overdose of the antihistamine medicine diphenhydramine (commonly sold in the United States ...

  6. Drug overdose - Wikipedia

    en.wikipedia.org/wiki/Drug_overdose

    Fentanyl. 2 mg (white powder to the right) is a lethal dose in most people. [1] US penny is 19 mm (0.75 in) wide. A drug overdose (overdose or OD) is the ingestion or application of a drug or other substance in quantities much greater than are recommended. [2] [3] Typically the term is applied for cases when a risk to health is a potential ...

  7. United States drug overdose death rates and totals over time

    en.wikipedia.org/wiki/United_States_drug...

    Drug overdose deaths in the US per 100,000 people by state. [1] [2] A two milligram dose of fentanyl powder (on pencil tip) is a lethal amount for most people.[3]The United States Centers for Disease Control and Prevention (CDC) has data on drug overdose death rates and totals.

  8. Opioid epidemic in the United States - Wikipedia

    en.wikipedia.org/wiki/Opioid_epidemic_in_the...

    In the United States, there were approximately 109,600 drug-overdose-related deaths in the 12-month period ending January 31, 2023, at a rate of 300 deaths per day. [6] From 1999 to 2020, nearly 841,000 people died from drug overdoses, [ 7 ] with prescription and illicit opioids responsible for 500,000 of those deaths. [ 8 ]

  9. Reference dose - Wikipedia

    en.wikipedia.org/wiki/Reference_dose

    A reference dose is the United States Environmental Protection Agency's maximum acceptable oral dose of a toxic substance, "below which no adverse noncancer health effects should result from a lifetime of exposure". Reference doses have been most commonly determined for pesticides. The EPA defines an oral reference dose (abbreviated RfD) as: