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Validol, the anxiety medication containing a roughly 25% solution of menthol in menthyl isovalerate is prepared essentially in one step, in which the amount of menthol added before conducting the acid catalysed esterification is in an excess such that the resulting solution of the yielded ester has around 25% menthol, simplifying the procedure.
The equine version of Absorbine is sometimes used by humans, [22] though, anecdotally, its benefits in humans may be because the smell of menthol releases serotonin, or due to a placebo effect. [20] Earl Sloan was a US entrepreneur who made his initial fortune selling his father's horse liniment formula beginning in the period following the ...
Menthol has local anesthetic and counterirritant qualities, and it is widely used to relieve minor throat irritation. Menthol has been demonstrated to cause a subjective nasal decongestant effect without any objective decongestant action, and administration of menthol via a nasal inhaler in humans has also been shown to cause nasal congestion ...
The Hall Brothers company was founded in 1893 by Thomas Harold Hall and Norman Smith Hall. The cough drops were first made in the 1930s on Stanley Road, Whitefield, Lancashire. [2] The company was acquired by Warner-Lambert in 1964 with production moved to Dumers Lane, Radcliffe in 1970. Pfizer acquired Warner-Lambert in June 2000.
There are many different formulations developed since the first marketing authorisation in 1978. Ambroxol is available as syrup, tablets, pastilles, dry powder sachets, inhalation solution, drops and ampules as well as effervescent tablets. Ambroxol also provides pain relief in acute sore throat.
Luden's Throat Drops brand was sold by Hershey's to Pharmacia in 2001. In 2003, Pharmacia was acquired by Pfizer. [5] In 2006, Pfizer sold its consumer products division, including the Luden's line, to Johnson & Johnson. [2] As of 2008, packages of Luden's throat drops displayed the slogan "Trusted Luden's Care – Everyone needs a little TLC". [6]
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Non-menthol throat lozenges generally use either zinc gluconate glycine or pectin as an oral demulcent. Several brands of throat lozenges contain dextromethorphan. Other varieties such as Halls contain menthol, peppermint oil and/or spearmint as their active ingredient(s). Honey lozenges are also available.