Search results
Results from the WOW.Com Content Network
Meta-analysis is a method of synthesis of quantitative data from multiple independent studies addressing a common research question. An important part of this method ...
For normally distributed random variables inverse-variance weighted averages can also be derived as the maximum likelihood estimate for the true value. Furthermore, from a Bayesian perspective the posterior distribution for the true value given normally distributed observations and a flat prior is a normal distribution with the inverse-variance weighted average as a mean and variance ().
Under Fisher's method, two small p-values P 1 and P 2 combine to form a smaller p-value.The darkest boundary defines the region where the meta-analysis p-value is below 0.05.. For example, if both p-values are around 0.10, or if one is around 0.04 and one is around 0.25, the meta-analysis p-value is around 0
A meta-regression can be classified in the same way—meta-regression and network meta-regression—depending on the number of distinct treatments in the regression analysis. Meta-analysis (and meta-regression) is often placed at the top of the evidence hierarchy provided that the analysis consists of individual participant data of randomized ...
The area of each square is proportional to the study's weight in the meta-analysis. The overall meta-analysed measure of effect is often represented on the plot as a dashed vertical line. This meta-analysed measure of effect is commonly plotted as a diamond, the lateral points of which indicate confidence intervals for this estimate.
Meta-analysis is a method used to combine the results of different trials in order to obtain a quantitative synthesis. The size of individual clinical trials is often too small to detect treatment effects reliably. Meta-analysis increases the power of statistical analyses by pooling the results of all available trials.
The log diagnostic odds ratio is sometimes used in meta-analyses of diagnostic test accuracy studies due to its simplicity (being approximately normally distributed). [ 4 ] Traditional meta-analytic techniques such as inverse-variance weighting can be used to combine log diagnostic odds ratios computed from a number of data sources to produce ...
They relate to the validity of the often convenient assumption that the statistical properties of any one part of an overall dataset are the same as any other part. In meta-analysis, which combines the data from several studies, homogeneity measures the differences or similarities between the several studies (see also Study heterogeneity).