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  2. Metoprolol - Wikipedia

    en.wikipedia.org/wiki/Metoprolol

    Metoprolol, sold under the brand name Lopressor among others, is a medication used to treat angina, high blood pressure and a number of conditions involving an abnormally fast heart rate. [4] It is also used to prevent further heart problems after myocardial infarction and to prevent headaches in those with migraines . [ 4 ]

  3. Biopharmaceutics Classification System - Wikipedia

    en.wikipedia.org/wiki/Biopharmaceutics...

    Example: metoprolol, paracetamol [2] Those compounds are well absorbed and their absorption rate is usually higher than excretion. Class II – high permeability, low solubility. Example: glibenclamide, bicalutamide, ezetimibe, aceclofenac; The bioavailability of those products is limited by their

  4. Elimination rate constant - Wikipedia

    en.wikipedia.org/wiki/Elimination_rate_constant

    The elimination rate constant K or K e is a value used in pharmacokinetics to describe the rate at which a drug is removed from the human system. [1] It is often abbreviated K or K e. It is equivalent to the fraction of a substance that is removed per unit time measured at any particular instant and has units of T −1.

  5. Beta blocker - Wikipedia

    en.wikipedia.org/wiki/Beta_blocker

    Beta blockers are known primarily for their reductive effect on heart rate, although this is not the only mechanism of action of importance in congestive heart failure. [17] Beta blockers, in addition to their sympatholytic β 1 activity in the heart, influence the renin–angiotensin system at the kidneys.

  6. Pharmacokinetics - Wikipedia

    en.wikipedia.org/wiki/Pharmacokinetics

    Absorption rate constant: The rate at which a drug enters into the body for oral and other extravascular routes. ⁡ 0.693 h −1: Elimination half-‍life ...

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  8. Absorption rate constant - Wikipedia

    en.wikipedia.org/wiki/Absorption_rate_constant

    The absorption rate constant K a is a value used in pharmacokinetics to describe the rate at which a drug enters into the system. It is expressed in units of time −1. [1] The K a is related to the absorption half-life (t 1/2a) per the following equation: K a = ln(2) / t 1/2a. [1] K a values can typically only be found in research articles. [2]

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