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In neuroscience, Dale's principle (or Dale's law) is a rule attributed to the English neuroscientist Henry Hallett Dale. The principle basically states that a neuron performs the same chemical action at all of its synaptic connections to other cells, regardless of the identity of the target cell. However, there has been disagreement about the ...
Dale clearly saw the specificity of the "paralytic" effect of ergot for "the so-called myoneural junctions connected with the true sympathetic or thoracic-lumbar division of the autonomic nervous system"—the adrenoceptors. He also saw its specificity for the "myoneural junctions" mediating smooth muscle contraction as opposed to those ...
Sir Henry Hallett Dale (9 June 1875 – 23 July 1968) was an English pharmacologist and physiologist. [3] For his study of acetylcholine as agent in the chemical transmission of nerve pulses ( neurotransmission ) he shared the 1936 Nobel Prize in Physiology or Medicine with Otto Loewi .
Vasomotor refers to actions upon a blood vessel which alter its diameter. [ 1 ] [ 2 ] More specifically, it can refer to vasodilator action and vasoconstrictor action. Control
Skeletal muscle pump: Rhythmical contractions of limb muscles as occurs during normal activity such as walking, running, and swimming, promotes venous return.; Decreased venous capacitance: Sympathetic activation of veins decreases venous compliance, increases vasomotor tone, increases central venous pressure and promotes venous return indirectly by augmenting cardiac output through the Frank ...
Vasomotion is the spontaneous oscillation in tone of blood vessel walls, independent of heart beat, innervation or respiration. [1] While vasomotion was first observed by Thomas Wharton Jones in 1852, the complete mechanisms responsible for its generation and its physiological importance remain to be elucidated.
Controversial replay challenge reversal dooms U.S. beach volleyball duo. Jeff Eisenberg. July 31, 2021 at 7:18 PM.
We can consider as an example a positively charged ion, such as K +, and a negatively charged membrane, as it is commonly the case in most organisms. [4] [5] The membrane voltage opposes the flow of the potassium ions out of the cell and the ions can leave the interior of the cell only if they have sufficient thermal energy to overcome the energy barrier produced by the negative membrane ...