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4-Fluoroephedrine, also known as 4-fluoro-β-hydroxy-N-methylamphetamine, is a substituted phenethylamine, amphetamine, and β-hydroxyamphetamine derivative. [6] [1] It is the 4-fluoro analogue of ephedrine. [6] [1] The synthesis of 4-fluoroephedrine has been described. [7] It can serve as a precursor in the synthesis of 4-fluoromethamphetamine ...
Ephedrine promotes modest short-term weight loss, [24] specifically fat loss, but its long-term effects are unknown. [25] In mice, ephedrine is known to stimulate thermogenesis in the brown adipose tissue, but because adult humans have only small amounts of brown fat, thermogenesis is assumed to take place mostly in the skeletal muscle.
4-Fluoromethylphenidate was studied further along with other analogues of (±)-threo-methylphenidate (TMP) to assess their potential as anti-cocaine medications. 4F-MPH was reported as having an ED 50 mg/kg of 0.26 (0.18–0.36), regarding its efficacy as a substitute for cocaine, and a relative potency of 3.33 compared to methylphenidate for ...
4-Fluoroamphetamine is a releasing agent and reuptake inhibitor of dopamine, serotonin, and norepinephrine. [9] The respective EC 50 values are 2.0 x 10 −7 M, 7.3 x 10 −7 M, and 0.37 x 10 −7 M, while the IC 50 values are 7.7 x 10 −7 M, 68 x 10 −7 M, and 4.2 x 10 −7 M. [3]
[3] [4] [1] It is reported to be used in various over-the-counter cough and cold preparations throughout the world, including Japan. [1] The drug is an ephedrine-like sympathomimetic and activates α-and β-adrenergic receptors. [5] Chemically, it is a substituted amphetamine and is closely related to ephedrine. [3] [4]
4-FMA is considered a Schedule 9 substance in Australia under the Poisons Standard (October 2015). [6] A Schedule 9 substance is a substance which may be abused or misused, the manufacture, possession, sale or use of which should be prohibited by law except when required for medical or scientific research, or for analytical, teaching or training purposes with approval of Commonwealth and/or ...
February 4, 2025 at 9:04 PM If you’re stuck on today’s Wordle answer, we’re here to help—but beware of spoilers for Wordle 1327 ahead. Let's start with a few hints.
[4] [5] [6] It is taken by mouth. [1] Oxilofrine acts as a norepinephrine releasing agent and hence is an indirectly acting sympathomimetic. [7] [6] [8] It is a substituted amphetamine and is closely related to ephedrine (with oxilofrine also being known as 4-hydroxyephedrine). [4] [8] Oxilofrine was first developed in the 1930s. [9]