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The typical signs of malignant hyperthermia are due to a hypercatabolic state, which presents as a very high temperature, an increased heart rate and abnormally rapid breathing, increased carbon dioxide production, increased oxygen consumption, mixed acidosis, rigid muscles, and rhabdomyolysis. [5]
Hyperthermia from neurological disease may include little or no sweating, cardiovascular problems, and confusion or delirium. Other signs and symptoms vary. Accompanying dehydration can produce nausea, vomiting, headaches, and low blood pressure and the latter can lead to fainting or dizziness, especially if the standing position is assumed ...
Symptoms may also be mistaken for similarly presenting conditions such as malignant hyperthermia, serotonin syndrome, or withdrawal from illicit drugs such as alcohol, cocaine, or MDMA. [ 7 ] Neuroleptic malignant syndrome (NMS) usually presents with a "lead pipe rigidity" in which the muscles are stiffened and resistance is observed throughout ...
Other signs and symptoms of malignant hyperthermia include metabolic and respiratory acidosis, hyperkalemia, and cardiac arrhythmias. Akinetic mutism is a neurological disorder characterized by a decrease in goal-directed behavior and motivation; however, the patient has an intact level of consciousness. [ 54 ]
Photoradiation and hyperthermia are also used as treatment forms to kill or reduce malignant cells. A large portion of patients are at risk of death when diagnosed with malignancy as the disease has usually progressed for a number of years before detection.
Hyperthermia is defined as the condition where an individual's body temperature is elevated beyond normal parameters as a result of the failure of thermoregulatory processes. [19] Hyperthermia is a common symptom of conditions such as heat stroke, where it manifests as hot, dry skin or heavy perspiration. [32] Heat stroke itself can be devastating.
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Temperature measurement to discern hypothermia or fever, and to allow early detection of malignant hyperthermia. Electroencephalography, entropy monitoring, or other systems may be used to verify the depth of anaesthesia. This reduces the likelihood of anaesthesia awareness and of overdose.