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  2. Heart Condition (film) - Wikipedia

    en.wikipedia.org/wiki/Heart_Condition_(film)

    Heart Condition is a 1990 American comedy film starring Bob Hoskins, Denzel Washington and Chloe Webb. Denzel Washington stars as Napoleon Stone, a lawyer, and Bob Hoskins stars as Jack Moony, a police officer. The two rivals compete in the same work force area in their community to help bring down drug rate.

  3. Pacemaker current - Wikipedia

    en.wikipedia.org/wiki/Pacemaker_current

    The funny current is highly expressed in spontaneously active cardiac regions, such as the sinoatrial node (SAN, the natural pacemaker region), the atrioventricular node (AVN) and the Purkinje fibres of conduction tissue. The funny current is a mixed sodium–potassium current that activates upon hyperpolarization at voltages in the diastolic ...

  4. Cardiac action potential - Wikipedia

    en.wikipedia.org/wiki/Cardiac_action_potential

    In the heart's conduction system electrical activity that originates from the sinoatrial node (SAN) is propagated via the His-Purkinje network, the fastest conduction pathway within the heart. The electrical signal travels from the sinoatrial node, which stimulates the atria to contract, to the atrioventricular node (AVN) , which slows down ...

  5. Isovolumetric contraction - Wikipedia

    en.wikipedia.org/wiki/Isovolumetric_contraction

    The isovolumetric contraction phase lasts about 0.05 seconds, [1] but this short period of time is enough to build up a sufficiently high pressure that eventually overcomes that of the aorta and the pulmonary artery upon opening of the semilunar valves. This process, therefore, helps maintain the correct unidirectional flow of blood through the ...

  6. Myocardial contractility - Wikipedia

    en.wikipedia.org/wiki/Myocardial_contractility

    An increase in sympathetic stimulation to the heart increases contractility and heart rate. An increase in contractility tends to increase stroke volume and thus a secondary increase in preload. An increase in preload results in an increased force of contraction by Starling's law of the heart; this does not require a change in contractility.

  7. Cardiac pacemaker - Wikipedia

    en.wikipedia.org/wiki/Cardiac_pacemaker

    It employs pacemaker cells that produce electrical impulses, known as cardiac action potentials, which control the rate of contraction of the cardiac muscle, that is, the heart rate. In most humans, these cells are concentrated in the sinoatrial (SA) node, the primary pacemaker, which regulates the heart’s sinus rhythm.

  8. Cardiac contractility modulation - Wikipedia

    en.wikipedia.org/wiki/Cardiac_contractility...

    The FDA approved the OPTIMIZER Smart System, which delivers cardiac contractility modulation therapy, as indicated to improve 6-minute hall walk distance, quality of life, and functional status of NYHA Class III heart failure patients who remain symptomatic despite guideline directed medical therapy, who are in normal sinus rhythm, are not indicated for cardiac resynchronization therapy, and ...

  9. Fibrillation - Wikipedia

    en.wikipedia.org/wiki/Fibrillation

    This happens when muscle fibers lose contact with their innervating axon producing a spontaneous action potential, "fibrillation potential" that results in the muscle fiber's contraction. These contractions are not visible under the skin and are detectable through needle electromyography (EMG) and ultrasound. [ 8 ]