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A genetic correlation between two traits will tend to produce phenotypic correlations – e.g. the genetic correlation between intelligence and SES [16] or education and family SES [37] implies that intelligence/SES will also correlate phenotypically. The phenotypic correlation will be limited by the degree of genetic correlation and also by ...
Falconer's formula assumes the equal contribution of environmental factors in MZ pairs and DZ pairs. Therefore, additional phenotypic correlation between the two pairs is due to genetic factors. Subtracting the correlation of the DZ pairs from MZ pairs yields the variance in phenotypes contributed by genetic factors. [4]
Similar genotypic changes may result in similar phenotypic alterations, even across a wide range of species. [1] The genotype–phenotype distinction is drawn in genetics. The "genotype" is an organism's full hereditary information. The "phenotype" is an organism's actual observed properties, such as morphology, development, or behavior.
When there is only additive gene action, this sibling phenotypic correlation is an index of familiarity – the sum of half the additive genetic variance plus full effect of the common environment. It thus places an upper limit on additive heritability of twice the full-Sib phenotypic correlation.
Phenotypic integration is a metric for measuring the correlation of multiple functionally-related traits to each other. [1] Complex phenotypes often require multiple traits working together in order to function properly. Phenotypic integration is significant because it provides an explanation as to how phenotypes are sustained by relationships ...
Phenotypic variation (due to underlying heritable genetic variation) is a fundamental prerequisite for evolution by natural selection. It is the living organism as a whole that contributes (or not) to the next generation, so natural selection affects the genetic structure of a population indirectly via the contribution of phenotypes.
A phenotypic trait is an obvious, observable, and measurable characteristic of an organism; it is the expression of genes in an observable way. An example of a phenotypic trait is a specific hair color or eye color. Underlying genes, that make up the genotype, determine the hair color, but the hair color observed is the phenotype.
The first phenotypic disease network was constructed by Hidalgo et al. (2009) [1] to help understand the origins of many diseases and the links between them. Hidalgo et al. (2009) defined diseases as specific sets of phenotypes that affect one or several physiological systems, and compiled data on pairwise comorbidity correlations for more than 10,000 diseases reconstructed from over 30 ...