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Lysosomal acid lipase deficiencies occur when a person has defects (mutations) in both copies of the LIPA gene. Each parent of a person with LAL deficiency carries one copy of the defective LIPA gene. With every pregnancy, parents with a son or daughter affected by LAL deficiency have a 1 in 4 (25%) chance of having another affected child.
Lipoprotein lipase deficiency is a genetic disorder in which a person has a defective gene for lipoprotein lipase, which leads to very high triglycerides, which in turn causes stomach pain and deposits of fat under the skin, and which can lead to problems with the pancreas and liver, which in turn can lead to diabetes.
It’s common knowledge that managing your weight keeps you healthy now and as you get older. In fact, obesity contributes to several health conditions, including heart disease, stroke, type 2 ...
Also known as androgenetic alopecia, female pattern hair loss (FPHL) will affect 40 percent of women by age 50, according to Journal of the American Academy of Dermatology. This chronic and slow ...
Lipoprotein lipase deficiency leads to hypertriglyceridemia (elevated levels of triglycerides in the bloodstream). [35] In mice, overexpression of LPL has been shown to cause insulin resistance, [36] [37] and to promote obesity. [30] A high adipose tissue LPL response to a high-carbohydrate diet may predispose toward fat gain.
Hair loss can be caused by many factors, from alopecia to pregnancy to poor diet. Here, doctors discuss how to prevent hair loss and the best regrowth treatments.
"There are many causes of hair loss, but by far the most common cause is hereditary hair loss with age," Phipps says. "Some men and women have a genetic predisposition for the hair follicles to be ...
In those with loss-of-function variants in both copies of ANGPTL3, low LDL-C, low HDL-C, and low triglycerides are seen ("familial combined hypolipidemia"). [ 3 ] Hooft disease is a rare condition evidenced by low blood lipid level, red rash and mental and physical retardation.