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Sodium thiosulfate has been observed to help in the treatment of a rare systemic fibrosis condition caused by gadolinium-based contrast media in patients with kidney failure. [ 19 ] The compound can also be used to measure the volume of extracellular body fluid and the renal glomerular filtration rate .
Sodium thiosulfate is used in the treatment of cyanide poisoning. [3] It is on the World Health Organization's List of Essential Medicines. [4] [5] Other uses include topical treatment of ringworm and tinea versicolor, [3] [6] and treating some side effects of hemodialysis [7] and chemotherapy.
Sodium nitrite/sodium thiosulfate, sold under the brand name Nithiodote, is a fixed-dose combination medication used as an antidote for cyanide poisoning. [1] It contains sodium thiosulfate and sodium nitrite. [1] It is given by intravenous infusion into a vein. [1] It was approved for medical use in the United States in January 2011. [2]
Chaparral (or Larrea tridentata) – a plant used to make a herbal remedy which is sold as cancer treatment. Cancer Research UK state that: "We don't recommend that you take chaparral to treat or prevent any type of cancer." [67] Chlorella – a type of algae promoted for its health-giving properties, including a claimed ability to treat cancer ...
The American Association for Cancer Research has recently written that research shows an association between fungi, including Candida, and cancer but has not determined causation. [5] The site does not endorse any cures, including treatment with sodium bicarbonate. Quackwatch lists sodium bicarbonate injections as a "dubious treatment". [6]
Sodium thiosulfate is commonly prescribed for treatment in patients with calciphylaxis. The actual mechanism of the drug is unknown, but several explanations have been proposed, including chelation of calcium, vasodilation, antioxidant properties, and restoration of endothelial function.
Research on the medicinal effects of gold began in 1935, [2] primarily to reduce inflammation and to slow disease progression in patients with rheumatoid arthritis. The use of gold compounds has decreased since the 1980s because of numerous side effects and monitoring requirements, limited efficacy, and very slow onset of action.
An example is sodium thiosulfate, which the US FDA approved in 2022 to minimise the risk of ototoxicity and hearing loss in newborn, child, and adolescent cancer patients receiving cisplatin. [ 29 ] [ 30 ] [ 31 ] Other agents being investigated for their potential to reduce ototoxicity include D-methionine and L-N-acetylcysteine . [ 3 ]