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Hypoxic ventilatory response (HVR) is the increase in ventilation induced by hypoxia that allows the body to take in and transport lower concentrations of oxygen at higher rates. It is initially elevated in lowlanders who travel to high altitude, but reduces significantly over time as people acclimatize .
The hypoxicator allows automated and pre-programmed delivery of the required hypoxic and hyperoxic or normoxic air and safety monitoring. The therapeutic range of arterial oxygen desaturation for IHT is SpO 2 = 75% - 88% and must be selected based upon the recommendation of a medical specialist.
Hypoxic air systems can be integrated with the building management system and can include systems to recover the heat generated by the hypoxic air generator that, would otherwise be wasted. [ 5 ] Air with low oxygen concentration is transported to the protected volumes through dedicated pipes or, more simply, via an existing ventilation system .
By redirecting blood flow from poorly-ventilated lung regions to well-ventilated lung regions, HPV is thought to be the primary mechanism underlying ventilation/perfusion matching. [1] [2] The process might initially seem counterintuitive, as low oxygen levels might theoretically stimulate increased blood flow to the lungs to increase gas exchange.
The control of ventilation is the physiological mechanisms involved in the control of breathing, which is the movement of air into and out of the lungs. Ventilation facilitates respiration. Respiration refers to the utilization of oxygen and balancing of carbon dioxide by the body as a whole, or by individual cells in cellular respiration. [1]
Acute respiratory acidosis occurs when an abrupt failure of ventilation occurs. This failure in ventilation may be caused by depression of the central respiratory center by cerebral disease or drugs, inability to ventilate adequately due to neuromuscular disease (e.g., myasthenia gravis, amyotrophic lateral sclerosis, Guillain–Barré syndrome, muscular dystrophy), or airway obstruction ...
A controlled F I O 2 is particularly important for patients whose ventilation is dependent on hypoxic drive, [5] as may be seen in patients with chronic obstructive pulmonary disease. Administration of too much oxygen may lead to a reduction in their respiratory rate and retention of carbon dioxide, and ultimately to reduced consciousness or ...
Artificial ventilation or respiration is when a machine assists in a metabolic process to exchange gases in the body by pulmonary ventilation, external respiration, and internal respiration. [1] A machine called a ventilator provides the person air manually by moving air in and out of the lungs when an individual is unable to breathe on their own.