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Cefoperazone/sulbactam is a combination drug used as an antibiotic. It is effective for the treatment of urinary tract infections . [ 2 ] It contains cefoperazone , a β-lactam antibiotic , and sulbactam , a β-lactamase inhibitor , which helps prevent bacteria from breaking down cefoperazone.
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Cefoperazone contains an N-methylthiotetrazole (NMTT or 1-MTT) side chain.As the antibiotic is broken down in the body, it releases free NMTT, which can cause hypoprothrombinemia (likely due to inhibition of the enzyme vitamin K epoxide reductase) and a reaction with ethanol similar to that produced by disulfiram (Antabuse effect), due to inhibition of aldehyde dehydrogenase.
ATC code J01 Antibacterials for systemic use is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
Newmark launched craigslist.org in 1996, where people could exchange information, mostly without charge. [12] It started as a newsletter about San Francisco events. [ 14 ] He operated it as a hobby while continuing to work as a software engineer until 1999 when he incorporated Craigslist as a private for-profit company. [ 15 ]
From January 2008 to December 2012, if you bought shares in companies when Linda Fayne Levinson joined the board, and sold them when she left, you would have a -6.7 percent return on your investment, compared to a -2.8 percent return from the S&P 500.
Drew Barrymore Dimitrios Kambouris/Getty Images for Albie Awards Drew Barrymore joked she’s “about to get off” dating apps after being catfished by a man pretending to be an NFL player.
The combination cefoperazone/sulbactam (Sulperazon) is available in many countries but not in the United States. [4] The co-packaged combination sulbactam/durlobactam was approved for medical use in the United States in May 2023. [5]