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A man with pellagra, which is caused by a chronic lack of vitamin B 3 in the diet. Severe deficiency of niacin in the diet causes the disease pellagra, characterized by diarrhea, sun-sensitive dermatitis involving hyperpigmentation and thickening of the skin (see image), inflammation of the mouth and tongue, delirium, dementia, and if left untreated, death. [7]
Example of a label showing the amount of niacin (Vitamin B3), and specifying to be niacinamide in the ingredient section.. The United States adopted in 1942 the terms niacin to nicotinic acid and niacinamide to nicotinamide to avoid references to nicotine, [12] [13] the terms were incorporated into the United States Adopted Name [14] that was created later in 1961.
It was a combination of the lipid-modifying drug/vitamin niacin in extended release form and the statin drug lovastatin (trade name Mevacor). The combination preparation was developed by Kos Pharmaceuticals, Inc., which was acquired by Abbott Laboratories in 2006, subsequently transferred to AbbVie Inc. when that company was spun off from ...
Pellagra is a disease caused by a lack of the vitamin niacin (vitamin B 3). [2] Symptoms include inflamed skin, diarrhea, dementia, and sores in the mouth. [1] Areas of the skin exposed to friction and radiation are typically affected first. [1] Over time affected skin may become darker, stiffen, peel, or bleed. [1] [3]
Nicotinamide (INN, BAN UK [2]) or niacinamide (USAN US) is a form of vitamin B 3 found in food and used as a dietary supplement and medication. [3] [4] [5] As a supplement, it is used orally (swallowed by mouth) to prevent and treat pellagra (niacin deficiency). [4]
NMN is found in fruits and vegetables such as edamame, broccoli, cabbage, cucumber and avocado at a concentration of about 1 mg per 100g, [16] [17] [18] making these natural sources impractical to acquire the quantities needed to accomplish the dosing currently being investigated for NMN as a pharmaceutical.
Niacin refers to the vitamers of vitamin B 3. Niacin may also refer to: Niacin, portmanteau of nicotinic acid vitamin, one of the vitamin B 3 vitamers;
Vitamin C can be synthesized by some species but not by others. Vitamin B 12 is the only vitamin or nutrient not available from plant sources. The Food Fortification Initiative lists countries which have mandatory fortification programs for vitamins folic acid, niacin, vitamin A and vitamins B 1, B 2 and B 12. [9]
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