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  2. Align Technology - Wikipedia

    en.wikipedia.org/wiki/Align_Technology

    The Invisalign Express 10, which uses 10 aligners, was introduced in 2005. [14] Invisalign 1.5 was released in 2009. It was followed by Invisalign G3 in 2010 and G4 in 2011. Invisalign G3 and G4 were designed for more complex treatments. An Invisalign Express 5 version, which uses 5 aligners, was introduced in 2012. [15]

  3. Clear aligners - Wikipedia

    en.wikipedia.org/wiki/Clear_aligners

    Invisalign is manufactured by Align Technology, an American multinational medical-device company. The company's clear align system has been used to treat more than 12.2 million patients. [2] The company was founded in 1997 by Zia Chishti. Chishti conceived of the basic design of InvisAlign while an adult orthodontics patient.

  4. Zia Chishti - Wikipedia

    en.wikipedia.org/wiki/Zia_Chishti

    Zia Chishti was born as Wilson Lear in 1971 [4] in Bar Harbor, Maine. [9] His father, George Lear, was an American while his mother was Pakistani, and after the death of his father in 1974, [4] he and his mother moved to Lahore, Pakistan. [1]

  5. Prescription Drug User Fee Act - Wikipedia

    en.wikipedia.org/wiki/Prescription_Drug_User_Fee_Act

    In 2015, 132.5 full application equivalents (FAEs) were charged an application fee. FAEs are calculated by counting a full application as one FAE and an application not requiring clinical data or a clinical data supplement as half an FAE. An application that is withdrawn, or refused for filing, counts as one quarter of the original FAE.