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A prion / ˈ p r iː ɒ n / ⓘ is a misfolded protein that induces misfolding in normal variants of the same protein, leading to cellular death. Prions are responsible for prion diseases, known as transmissible spongiform encephalopathy (TSEs), which are fatal and transmissible neurodegenerative diseases affecting both humans and animals.
Asimov on Science Fiction (ISBN 0-586-05840-0) is a 1981 non-fiction work by American writer and scientist Isaac Asimov. It is a collection of short essays dealing with various aspects of science fiction. Many of the essays are (slightly edited versions of) editorials from Isaac Asimov's Science Fiction Magazine.
Boris Karloff in James Whale's 1931 film Frankenstein, based on Mary Shelley's 1818 novel.The monster is created by an unorthodox biology experiment.. Biology appears in fiction, especially but not only in science fiction, both in the shape of real aspects of the science, used as themes or plot devices, and in the form of fictional elements, whether fictional extensions or applications of ...
Self-replication is a fundamental feature of life. It was proposed that self-replication emerged in the evolution of life when a molecule similar to a double-stranded polynucleotide (possibly like RNA) dissociated into single-stranded polynucleotides and each of these acted as a template for synthesis of a complementary strand producing two double stranded copies. [4]
Speculative fiction in technology of reproduction may involve cloning and ectogenesis, i.e., artificial reproduction). [2] [3]The latter part of the 2000s decade has also seen an upswing of films and other fiction depicting emotional struggles of assisted reproductive technology in contemporary reality rather than being speculation.
On the Writing of Speculative Fiction" is an essay by American science fiction writer Robert A. Heinlein. It was first published in 1947, also appearing in Writing Science Fiction & Fantasy: 20 Dynamic Essays By the Field's Top Professionals in 1993, and The Nonfiction of Robert Heinlein: Volume I in 2011.
The subsequent demonstration that human prion diseases were transmissible reinforced the importance of spongiform change as a diagnostic feature, reflected in the use of the term "spongiform encephalopathy" for this group of disorders. Prions appear to be most infectious when in direct contact with affected tissues.
Creutzfeldt–Jakob disease (CJD), also known as subacute spongiform encephalopathy or neurocognitive disorder due to prion disease, is a fatal neurodegenerative disease. [ 4 ] [ 1 ] Early symptoms include memory problems, behavioral changes, poor coordination, and visual disturbances. [ 4 ]