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Regular blood tests are recommended to verify the appropriateness of the dose. [1] They contain a mixture of thyroxine (T4) and triiodothyronine (T3). [1] Desiccated thyroid has been used since the late 1800s. [3] It is usually made from pigs, sheep, or cows. [4] It is available as a generic medication. [1]
ATC code H03 Thyroid therapy is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
Levothyroxine, also known as L-thyroxine, is a synthetic form of the thyroid hormone thyroxine (T 4). [5] [8] It is used to treat thyroid hormone deficiency (hypothyroidism), including a severe form known as myxedema coma. [5] It may also be used to treat and prevent certain types of thyroid tumors. [5] It is not indicated for weight loss. [5]
Liothyronine may be used when there is an impaired conversion of T 4 to T 3 in peripheral tissues. [1] The dose of liothyronine for hypothyroidism is a lower amount than levothyroxine due it being a higher concentrated synthetic medication. [1] About 25 μg of liothyronine is equivalent to 100 μg of levothyroxine. [2]
The thyroid system of the thyroid hormones T 3 and T 4 [1] Thyroid hormones are any hormones produced and released by the thyroid gland, namely triiodothyronine (T 3) and thyroxine (T 4). They are tyrosine-based hormones that are primarily responsible for regulation of metabolism. T 3 and T 4 are partially composed of iodine, derived from food. [2]
Levothyroxine dosing to normalise TSH is based on the amount of residual endogenous thyroid function and the patient’s weight, particularly lean body mass. [15] Usually the dose prescribed ranges from 1.6 mcg/kg to 1.8 mcg/kg, but can be adjusted based upon each patient. [10]
Thyroid hormone replacement with levothyroxine treats hypothyroidism. [3] Medical professionals adjust the dose according to symptoms and normalization of the thyroxine and TSH levels. [3] Thyroid medication is safe in pregnancy. [3] Although an adequate amount of dietary iodine is important, too much may worsen specific forms of hypothyroidism ...
An equianalgesic chart can be a useful tool, but the user must take care to correct for all relevant variables such as route of administration, cross tolerance, half-life and the bioavailability of a drug. [5] For example, the narcotic levorphanol is 4–8 times stronger than morphine, but also has a much longer half-life. Simply switching the ...
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