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  2. Human iron metabolism - Wikipedia

    en.wikipedia.org/wiki/Human_iron_metabolism

    Iron can be stored in ferritin as ferric iron due to the ferroxidase activity of the ferritin heavy chain. [28] Dysfunctional ferritin may accumulate as hemosiderin, which can be problematic in cases of iron overload. [29] The ferritin storage iron pool is much larger than the labile iron pool, ranging in concentration from 0.7 mM to 3.6 mM. [25]

  3. Latent iron deficiency - Wikipedia

    en.wikipedia.org/wiki/Latent_Iron_Deficiency

    The ideal is to increase the body's iron deposits, measured as levels of ferritin in serum, with the aim of reaching a ferritin value between 30 and 100 ng/mL. A clinical study has shown an increase in ferritin levels in those taking iron compared with others receiving a placebo. [11]

  4. Ferritin - Wikipedia

    en.wikipedia.org/wiki/Ferritin

    Ferritin genes are highly conserved between species. All vertebrate ferritin genes have three introns and four exons. [8] In human ferritin, introns are present between amino acid residues 14 and 15, 34 and 35, and 82 and 83; in addition, there are one to two hundred untranslated bases at either end of the combined exons. [9]

  5. Acute-phase protein - Wikipedia

    en.wikipedia.org/wiki/Acute-phase_protein

    Positive acute-phase proteins serve (as part of the innate immune system) different physiological functions within the immune system.Some act to destroy or inhibit growth of microbes, e.g., C-reactive protein, mannose-binding protein, [3] complement factors, ferritin, ceruloplasmin, serum amyloid A and haptoglobin.

  6. Iron-deficiency anemia - Wikipedia

    en.wikipedia.org/wiki/Iron-deficiency_anemia

    Iron-deficiency anemia is anemia caused by a lack of iron. [3] Anemia is defined as a decrease in the number of red blood cells or the amount of hemoglobin in the blood. [3] When onset is slow, symptoms are often vague such as feeling tired, weak, short of breath, or having decreased ability to exercise. [1]

  7. Iron deficiency - Wikipedia

    en.wikipedia.org/wiki/Iron_deficiency

    Iron deficiency, or sideropenia, is the state in which a body lacks enough iron to supply its needs. Iron is present in all cells in the human body and has several vital functions, such as carrying oxygen to the tissues from the lungs as a key component of the hemoglobin protein, acting as a transport medium for electrons within the cells in the form of cytochromes, and facilitating oxygen ...

  8. Iron overload - Wikipedia

    en.wikipedia.org/wiki/Iron_overload

    Iron overload (also known as haemochromatosis or hemochromatosis) is the abnormal and increased accumulation of total iron in the body, leading to organ damage. [1] The primary mechanism of organ damage is oxidative stress, as elevated intracellular iron levels increase free radical formation via the Fenton reaction.

  9. Iron polymaltose - Wikipedia

    en.wikipedia.org/wiki/Iron_polymaltose

    Iron(III)-hydroxide polymaltose complex is a medication used to treat iron deficiency / iron deficiency anemia and belongs to the group of oral iron preparations.The preparation is a macromolecular complex, consisting of iron(III) hydroxide (trivalent iron, Fe 3+, Fe(OH) 3 ·H 2 O) and the carrier polymaltose and is available in solid form as a film-coated or chewable tablet and in liquid form ...

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