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Omeprazole, sold under the brand names Prilosec and Losec, among others, is a medication used in the treatment of gastroesophageal reflux disease (GERD), ...
A derivative of timoprazole, omeprazole, was discovered in 1979, and was the first of a new class of drug that control acid secretion in the stomach, a proton pump inhibitor (PPI). [11] [12] Addition of 5-methoxy-substitution to the benzimidazole moiety of omeprazole was also made and gave the compound much more stability at neutral pH. [6]
Esomeprazole, sold under the brand name Nexium [or Neksium] among others, [2] is a medication which reduces stomach acid. [11] It is used to treat gastroesophageal reflux disease, peptic ulcer disease, and Zollinger–Ellison syndrome. [11] [12] Its effectiveness is similar to that of other proton pump inhibitors (PPIs). [13]
Teva also agreed to sell its Plan B One-Step and its brands of emergency contraception to Foundation Consumer Healthcare for $675 million in cash. Combined annual net sales of these products were $140 million last year. [82] It also sold Paragard to a unit of Cooper Companies Inc (COO.N) for $1.1 billion. [82]
English: Skeletal formula of omeprazole (original brand names Losec and Prilosec)—a widely used proton pump inhibitor. Created with ChemDoodle 8.0.0.3b and Adobe Illustrator CC 2015 . Date
Two years before the omeprazole patent expired, AstraZeneca patented S-omeprazole in pure form, pointing out that since some people metabolise R-omeprazole slowly, pure S-omeprazole treatment would give higher dose efficiency and less variation between individuals. [128] In March 2001, the company began to market Nexium, as it would a brand new ...
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The company's first international move took it to Russia in 1992. There, Dr. Reddy's formed a joint venture with the country's biggest pharmaceuticals producer, Biomed.They pulled out in 1995 amid accusations of scandal, involving "a significant material loss due to the activities of Moscow's branch of Reddy's Labs with the help of Biomed's chief executive". [8]
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