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D-Phenylalanine (DPA, D-Phe), sold under the brand names Deprenon, Sabiben, and Sabiden, is an enantiomer of phenylalanine which is described as an antidepressant and is marketed as a prescription drug for medical use in Argentina. [1] [2] The medication has been marketed since at least the 1970s [3] and continued to be available by the 2000s. [1]
Phenylalanine is a precursor for tyrosine, the monoamine neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline), and the biological pigment melanin. It is encoded by the messenger RNA codons UUU and UUC. Phenylalanine is found naturally in the milk of mammals.
Pegvaliase, sold under the brand name Palynziq, is a medication used for the treatment of the genetic disease phenylketonuria. [5] [9] [10] It is a phenylalanine (Phe)‑metabolizing enzyme. [5]
Regular, low-impact exercise is one of the best ways to manage knee pain naturally. Activities like swimming, cycling, and walking increase blood flow, which helps reduce inflammation and promotes ...
One is that the meditation-based pain relief was less effective in men when the opioid system was blocked, which suggested that they tend to rely on the body’s opioid production to reduce pain.
A diet that is low in phenylalanine but does not include protein substitutes may also fail to lower blood Phe levels, since a nutritionally insufficient diet may also trigger catabolism. For all these reasons, the prescription formula is an important part of the treatment for patients with classic PKU. [citation needed]
Applying peppermint oil to your forehead and temple can help with headaches, says Lovins. This may be because menthol increases blood flow and provides a cooling sensation, which may help reduce pain.
Lactoylphenylalanine, or Lac-Phe, is a metabolite generated by intense exercise. [1] [2] [3] In mice, high levels of Lac-Phe in the blood cause a decrease of food intake [1] and in humans, its production has been shown to correlate with adipose tissue loss during an endurance exercise intervention. [4]
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