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The odor detection threshold for phosgene is 0.4 ppm, four times the threshold limit value (time weighted average). Its high toxicity arises from the action of the phosgene on the −OH , −NH 2 and −SH groups of the proteins in pulmonary alveoli (the site of gas exchange), respectively forming ester, amide and thioester functional groups in ...
Many gases have toxic properties, which are often assessed using the LC 50 (median lethal concentration) measure. In the United States, many of these gases have been assigned an NFPA 704 health rating of 4 (may be fatal) or 3 (may cause serious or permanent injury), and/or exposure limits (TLV, TWA/PEL, STEL, or REL) determined by the ACGIH professional association.
Schedules 2 and 3 chemicals produced on their territory must also be reported in the annual statement insofar as the quantity thereof has exceeded a certain threshold value. [8] With a few exceptions, only annually produced quantities above 100 kg of List 2 substances from Part A or 1000 kg of a precursor from Part B must be reported to the ...
Phosgene is considered safe at 0.1 parts per million during an eight-hour exposure, or 0.2 ppm for a 15-minute exposure. ... The eight-hour exposure threshold would have to be even lower when ...
Personal protective equipment for IDLH conditions: pressure-demand self-contained breathing apparatus with a full facepiece. If the concentration of harmful substances is IDLH, the worker must use the most reliable respirators.
40 C.F.R.: Appendix A to Part 355—The List of Extremely Hazardous Substances and Their Threshold Planning Quantities (PDF) (July 1, 2008 ed.), Government Printing Office, archived from the original (PDF) on 2012-02-25
Traces of a toxic, colorless gas were found at the headquarters of Sweden’s security agency where a suspected gas leak last week forced authorities to evacuate some 500 people from the facility ...
Second, as one moves from shorter exposures to longer (left to right in the same row), the overall concentration allowed decreases due to the effects of cumulative dose. This is not always the case for AEGL-1 values, however, since they represent a threshold for non-disabling outcomes and sometimes only depend on air concentration. [3]