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Cerebrospinal fluid (CSF) is a clear, colorless transcellular body fluid found within the meningeal tissue that surrounds the vertebrate brain and spinal cord, and in the ventricles of the brain. CSF is mostly produced by specialized ependymal cells in the choroid plexuses of the ventricles of the brain, and absorbed in the arachnoid granulations .
Cerebrospinal fluid is produced by the choroid plexus in the ventricles of the brain and contained by the dura and arachnoid layers of the meninges. [23] [42] [64] The brain floats in CSF, which also transports nutrients to the brain and spinal cord. As holes form in the spinal dura mater, CSF leaks out into the surrounding space.
It allows blood to drain from the lateral aspects of the anterior cerebral hemispheres to the confluence of sinuses. Cerebrospinal fluid drains through arachnoid granulations into the superior sagittal sinus and is returned to the venous circulation .
A lumbar subcutaneous shunt (LS shunt) differs from these types of shunt in that the cerebrospinal fluid drains into the potential space immediately under the skin. A narrow tube is inserted into the subarachnoid space in the lumbar part of the back during a lumbar puncture.
A cerebral shunt is a device permanently implanted inside the head and body to drain excess fluid away from the brain. They are commonly used to treat hydrocephalus, the swelling of the brain due to excess buildup of cerebrospinal fluid (CSF).
Arachnoid granulations (also arachnoid villi, and Pacchionian granulations or bodies) are small outpouchings of the arachnoid mater and subarachnoid space into the dural venous sinuses of the brain. The granulations are thought to mediate the draining of cerebrospinal fluid (CSF) from the subarachnoid space into the venous system. [1]
Prior to the discovery of true meningeal lymphatic vessels, it was generally believed that the mammalian CNS did not contain a lymphatic system and thus relied upon alternative routes of waste clearance such as the glymphatic system, [8] a cerebrospinal fluid (CSF) drainage pathway under the cribriform plate and into the lymphatics of the nasal ...
According to this model, cerebrospinal fluid (CSF), an ultrafiltrated plasma fluid secreted by choroid plexuses in the cerebral ventricles, flows into the paravascular space around cerebral arteries, contacts and mixes with interstitial fluid (ISF) and solutes within the brain parenchyma, and exits via the cerebral venous paravascular spaces ...