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Shingles, also known as herpes zoster or zona, [6] is a viral disease characterized by a painful skin rash with blisters in a localized area. [2] [7] Typically the rash occurs in a single, wide mark either on the left or right side of the body or face. [1]
So the pain is "referred to" the related dermatomes of the same spinal segment. [3] Viruses that lie dormant in nerve ganglia (e.g. varicella zoster virus, which causes both chickenpox and shingles), often cause either pain, rash or both in a pattern defined by a dermatome (a zosteriform pattern). However, the symptoms may not appear across the ...
Years or decades later, shingles occurs when virions in a single ganglion reactivate, travel down nerve fibres and infect the skin around the nerve. The shingles rash is restricted to the area of skin supplied by a single spinal nerve, termed the dermatome. Exactly how VZV remains latent in the body, and subsequently reactivates, is unclear.
Varicella zoster virus is known to recur (after its initial presentation as chicken pox) as herpes zoster ("shingles"). Chicken pox appears nearly everywhere on the body, but herpes zoster tends to follow one or two dermatomes; for example, the eruptions may appear along the bra line, on either or both sides of the patient. [citation needed]
Postherpetic neuralgia (PHN) is neuropathic pain that occurs due to damage to a peripheral nerve caused by the reactivation of the varicella zoster virus (herpes zoster, also known as shingles). PHN is defined as pain in a dermatomal distribution that lasts for at least 90 days after an outbreak of herpes zoster. [ 1 ]
He eventually left his post at the rehabilitation facility in 2011. “I was stuck in an abstinence model that didn’t work,” Kalfas said. Administrators of the facility “really need to be confronted with their success rates. In AA, the definition of insanity is doing the same thing over and over again and expecting a different result.
Blaschko lines follow embryotic cell migration patterns and are seen in some mosaic genetic disorders such as incontinentia pigmenti and pigment mosaicism. Dermatomal distributions are lines on the skin surface following the distribution of spinal nerve roots. The rash caused by herpes zoster follows such dermatomal lines. [citation needed]
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