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HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-coenzyme A reductase, official symbol HMGCR) is the rate-controlling enzyme (NADH-dependent, EC 1.1.1.88; NADPH-dependent, EC 1.1.1.34) of the mevalonate pathway, the metabolic pathway that produces cholesterol and other isoprenoids. HMGCR catalyzes the conversion of HMG-CoA to mevalonic acid, a ...
Cholesterol is the principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils. [3][4] Cholesterol is biosynthesized by all animal cells [citation needed] and is an essential structural and signaling component of animal cell membranes.
Cyclodextrin. Chemical structure of the three main types of cyclodextrins. Cyclodextrins are a family of cyclic oligosaccharides, consisting of a macrocyclic ring of glucose subunits joined by α-1,4 glycosidic bonds. Cyclodextrins are produced from starch by enzymatic conversion. They are used in food, pharmaceutical, drug delivery, and ...
Polysaccharide. 3D structure of cellulose, a beta-glucan polysaccharide. Amylose is a linear polymer of glucose mainly linked with α (1→4) bonds. It can be made of several thousands of glucose units. It is one of the two components of starch, the other being amylopectin. Polysaccharides (/ ˌpɒliˈsækəraɪd /), or polycarbohydrates, are ...
Beta-glucan. Cellulose is an example of a (1→4)-β- D -glucan composed of glucose units. Beta-glucans, β-glucans comprise a group of β- D -glucose polysaccharides (glucans) naturally occurring in the cell walls of cereals, bacteria, and fungi, with significantly differing physicochemical properties dependent on source.
Glucose is a sugar with the molecular formula C 6 H 12 O 6. Glucose is overall the most abundant monosaccharide, [4] a subcategory of carbohydrates. Glucose is mainly made by plants and most algae during photosynthesis from water and carbon dioxide, using energy from sunlight.
Structures of some common lipids. At the top are cholesterol [1] and oleic acid. [2]: 328 The middle structure is a triglyceride composed of oleoyl, stearoyl, and palmitoyl chains attached to a glycerol backbone. At the bottom is the common phospholipid phosphatidylcholine.
Lipoprotein. Structure of a chylomicron (the largest lipoprotein). ApoA, ApoB, ApoC, ApoE are apolipoproteins; green particles are phospholipids; T is triglyceride; C is cholesterol ester. A lipoprotein is a biochemical assembly whose primary function is to transport hydrophobic lipid (also known as fat) molecules in water, as in blood plasma ...