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  2. Population genetics - Wikipedia

    en.wikipedia.org/wiki/Population_genetics

    The effect of genetic drift is larger for alleles present in few copies than when an allele is present in many copies. The population genetics of genetic drift are described using either branching processes or a diffusion equation describing changes in allele frequency. [ 43 ]

  3. Major histocompatibility complex - Wikipedia

    en.wikipedia.org/wiki/Major_histocompatibility...

    The MHC variation in the human population is high, at least 350 alleles for HLA-A genes, 620 alleles for HLA-B, 400 alleles for DR, and 90 alleles for DQ. Any two individuals who are not identical twins, triplets, or higher order multiple births, will express differing MHC molecules.

  4. Allele - Wikipedia

    en.wikipedia.org/wiki/Allele

    Allele. An allele[1], or allelomorph, is a variant of the sequence of nucleotides at a particular location, or locus, on a DNA molecule. [2] Alleles can differ at a single position through single nucleotide polymorphisms (SNP), [3] but they can also have insertions and deletions of up to several thousand base pairs. [4]

  5. Allele frequency - Wikipedia

    en.wikipedia.org/wiki/Allele_frequency

    Allele frequency. Allele frequency, or gene frequency, is the relative frequency of an allele (variant of a gene) at a particular locus in a population, expressed as a fraction or percentage. [1] Specifically, it is the fraction of all chromosomes in the population that carry that allele over the total population or sample size.

  6. Genetic diversity - Wikipedia

    en.wikipedia.org/wiki/Genetic_diversity

    Natural selection acts on adaptive genes which allows the organisms to evolve. [7] The rate of evolution on adaptive genes is greater than on neutral genes due to the influence of selection. [8] However, it has been difficult to identify alleles for adaptive genes and thus adaptive genetic diversity is most often measured indirectly. [7]

  7. Natural selection - Wikipedia

    en.wikipedia.org/wiki/Natural_selection

    Natural selection is the differential survival and reproduction of individuals due to differences in phenotype. It is a key mechanism of evolution, the change in the heritable traits characteristic of a population over generations. Charles Darwin popularised the term "natural selection", contrasting it with artificial selection, which is ...

  8. Recent human evolution - Wikipedia

    en.wikipedia.org/wiki/Recent_human_evolution

    e. Recent human evolution refers to evolutionary adaptation, sexual and natural selection, and genetic drift within Homo sapiens populations, since their separation and dispersal in the Middle Paleolithic about 50,000 years ago. Contrary to popular belief, not only are humans still evolving, their evolution since the dawn of agriculture is ...

  9. Allele frequency spectrum - Wikipedia

    en.wikipedia.org/wiki/Allele_frequency_spectrum

    In population genetics, the allele frequency spectrum, sometimes called the site frequency spectrum, is the distribution of the allele frequencies of a given set of loci (often SNPs) in a population or sample. [1][2][3][4] Because an allele frequency spectrum is often a summary of or compared to sequenced samples of the whole population, it is ...