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The human body's own cartilage is still the best material for lining knee joints. This drives efforts to develop ways of using a person's own cells to grow, or re-grow cartilage tissue to replace missing or damaged cartilage. One cell-based replacement technique is called autologous chondrocyte implantation (ACI) or autologous chondrocyte ...
Arthritis of the knee is typically a particularly debilitating form of arthritis. [1] The knee may become affected by almost any form of arthritis. [2] The word arthritis refers to inflammation of the joints. [3][4] Types of arthritis include those related to wear and tear of cartilage, such as osteoarthritis, to those associated with ...
In 2020, Merck reported 5-year follow-up data from the Phase 2 clinical trial for knee osteoarthritis (OA). The placebo controlled, multi-center study demonstrated that sprifermin was able to promote statistically significant improvement in cartilage thickness relative to control in a dose-dependent manner, meeting the primary endpoint of the study. [5]
Microfracture surgery. Left knee-joint from behind, showing interior ligaments. (Lateral meniscus and medial meniscus are cartilage.) Microfracture surgery is an articular cartilage repair surgical technique that works by creating tiny fractures in the underlying bone. This causes new cartilage to develop from a so-called super-clot.
Osteoarthritis (OA) is a type of degenerative joint disease that results from breakdown of joint cartilage and underlying bone. [5][6] It is believed to be the fourth leading cause of disability in the world, affecting 1 in 7 adults in the United States alone. [7] The most common symptoms are joint pain and stiffness. [1]
Meniscal cartilage replacement therapy. Head of right tibia seen from above, showing menisci and attachments of ligaments. [edit on Wikidata] Left knee-joint from behind, showing interior ligaments. Meniscal cartilage replacement therapy is surgical replacement of the meniscus of the knee as a treatment for where the meniscus is so damaged that ...
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