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Collagen (/ ˈkɒlədʒən /) is the main structural protein in the extracellular matrix of a body's various connective tissues. As the main component of connective tissue, it is the most abundant protein in mammals. [1] 25% to 35% of a mammalian body's protein content is collagen.
ECM. MeSH. D005109. TH. H2.00.03.0.02001. Anatomical terms of microanatomy. [edit on Wikidata] In biology, the extracellular matrix (ECM), [1][2] also called intercellular matrix (ICM), is a network consisting of extracellular macromolecules and minerals, such as collagen, enzymes, glycoproteins and hydroxyapatite that provide structural and ...
Bone mineral (also called inorganic bone phase, bone salt, or bone apatite) is the inorganic component of bone tissue. It gives bones their compressive strength. Bone mineral is formed predominantly from carbonated hydroxyapatite [1][2] with lower crystallinity. [1][3] Bone mineral is formed from globular and plate structures [3][4] distributed ...
Bone morphogenetic proteins (BMPs) are a group of growth factors also known as cytokines and as metabologens. [1] Professor Marshall Urist and Professor Hari Reddi discovered their ability to induce the formation of bone and cartilage, BMPs are now considered to constitute a group of pivotal morphogenetic signals, orchestrating tissue architecture throughout the body.
Ossein is the organic extracellular matrix of bone, which is made of 95% collagen. This substance is used in industry for the production of gelatin and bone glue. In the early 20th century, bones were found to consist of three types of proteins: ossein (collagens), osseomucoid (proteoglycans) and osseoalbuminoid (elastin). [1]
The active osteoblast produces substantial collagen type I. About 10% of the bone matrix is collagen with the balance mineral. [27] The osteoblast's nucleus is spherical and large. An active osteoblast is characterized morphologically by a prominent Golgi apparatus that appears histologically as a clear zone adjacent to the nucleus. The ...
Osteophagy. A bull chews on a bone of another cow. Osteophagy is the practice in which animals, usually herbivores, consume bones. Most vegetation around the world lacks sufficient amounts of phosphate. [1] Phosphorus is an essential mineral for all animals, as it plays a major role in the formation of the skeletal system, and is necessary for ...
a ground substance made of other organic compounds; The collagen and hydroxyapatite are held together by a strong protein-mineral bond that provides bone with its strength and its ability to remain long after the soft tissue of a body has been degraded. [4] The process that degrades bone is referred to as diagenesis.
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