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eNOS is a dimer containing two identical monomers of 140 kD constituted by a reductase domain, which displays binding sites for nicotinamide adenine dinucleotide phosphate (NADPH), flavin mononucleotide (FMN), and flavin adenine dinucleotide (FAD), and an oxidase domain, which displays binding sites for heme group, zinc, the cofactor tetrahydrobiopterin (), and the substrate L-arginine. [13]
Nitric oxide is mediated in mammals by the calcium-calmodulin controlled isoenzymes eNOS (endothelial NOS) and nNOS (neuronal NOS). [2] The inducible isoform, iNOS, involved in immune response, binds calmodulin at physiologically relevant concentrations, and produces NO as an immune defense mechanism, as NO is a free radical with an unpaired ...
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This is a selected list of freeware video games implemented as traditional executable files that must be downloaded and installed. Freeware games are games that are released as freeware and can be downloaded and played, free of charge, for an unlimited amount of time. This list does not include: Open source games (see List of open-source video ...
COMMAND. ACTION. Ctrl/⌘ + C. Select/highlight the text you want to copy, and then press this key combo. Ctrl/⌘ + F. Opens a search box to find a specific word, phrase, or figure on the page
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