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p-Nitrophenol, yellow solid is a precursor to the rice herbicide fluorodifen, the pesticide parathion, and the human analgesic paracetamol (also known as acetaminophen). The mononitrated phenols are often hydrogenated to the corresponding aminophenols that are also useful industrially.
When a substituent group is located ortho position to the carboxyl group in a substituted benzoic acid compound, the compound becomes more acidic surpassing the unmodified benzoic acid. Generally ortho-substituted benzoic acids are stronger acids than their meta and para isomers.
In organic chemistry, ortho acids are organic, hypothetical chemical compounds having the structure R−C(OH) 3 (R = alkyl or aryl). [1] Ortho acids themselves are unstable and cannot be isolated. However, ortho esters can be synthesized by the Pinner reaction, in which nitriles react with alcohols under acid catalysis: RCN + 3 R'OH → RC(OR ...
The prefixes ortho, meta, and para are all derived from Greek, meaning correct, following, and beside, respectively. The relationship to the current meaning is perhaps not obvious. The ortho description was historically used to designate the original compound, and an isomer was often called the meta compound.
4-Nitrophenol is an intermediate in the synthesis of paracetamol. It is reduced to 4-aminophenol, then acetylated with acetic anhydride. [6] 4-Nitrophenol is used as the precursor for the preparation of phenetidine and acetophenetidine, indicators, and raw materials for fungicides. Bioaccumulation of this compound rarely occurs.
It is staffed by 200 people and funded by more than $2.8 billion that goes directly to "disadvantaged, marginalized, and over-polluted communities," including support for projects that allow ...
Diagram showing the ortho, meta and para positions relative to a substituent X on a benzene ring. Both the regioselectivity—the diverse arene substitution patterns—and the speed of an electrophilic aromatic substitution are affected by the substituents already attached to the benzene ring.
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