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Autograft, tissue transplanted from one site to another on the same patient. An autograft reduces the risk of rejection but requires a second surgery site, adding pain, risk and possible longer aftercare. Xenograft, a transplant from another species; Isograft, a transplant from a genetically identical donor, such as an identical twin.
In orthopaedic medicine, a bone graft can be sourced from a patient's own bone in order to fill space and produce an osteogenic response in a bone defect. However, due to the donor-site morbidity associated with autograft, other methods such as bone allograft and bone morphogenetic proteins and synthetic graft materials are often used as alternatives.
A syngeneic graft is known as an isograft. [2] Related terms include: [citation needed] autogeneic, referring to autotransplantation, also termed autograft, (from one part of the body to another in the same person) allogeneic, referring to allotransplantation or an allograft (from other individual of same species).
This kind of graft is known as a vital bone graft. [citation needed] An autograft may also be performed without a solid bony structure, for example, using bone reamed from the anterior superior iliac spine. In this case, there is an osteoinductive and osteogenic action, however, there is no osteoconductive action, as there is no solid bony ...
Autograft: graft taken from one part of the body of an individual and transplanted onto another site in the same individual, e.g., skin graft. Isograft: graft taken from one individual and placed on another individual of the same genetic constitution, e.g., grafts between identical twins.
An allograft contains many of the beneficial characteristics of nerve autograft, such as three-dimensional microstructural scaffolding and protein components inherent to nerve tissue. [3] One of the adverse effects of nerve allotransplantation is the immunogenic response.
Hence, similar tissue from another part of the body that is in excess is sourced as the autograft. [10] [11] This can be seen in procedures like autologous orthopedic transplant, which remains the "gold standard" of bone grafting methods through extracting grafts from places like the iliac crest and transplanting them to the targeted fracture ...
When the human body is unable to regenerate the lost bone tissue, surgeons come in and replace the missing bone using autografts, allografts, and synthetic grafts (artificial bone). When comparing artificial bone to autograft and allograft, it is less invasive and more biocompatible since it avoids the risk of unknown viral infections. [3]